Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults

Aarón Salinas-Rodríguez, Julián Alfredo Fernández-Niño, Betty Manrique-Espinoza, Grea Litai Moreno-Banda, Ana Luisa Sosa-Ortiz, Zhengmin (Min) Qian, Hualiang Lin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Recent epidemiological research has shown that exposure to fine particulate pollution (PM 2.5 ) is associated with a reduction in cognitive function in older adults. However, primary evidence comes from high-income countries, and no specific studies have been conducted in low and middle-income countries where higher air pollution levels exist. Objectives: To estimate the association between the exposure to PM 2.5 and cognitive function in a nationally representative sample of older Mexican adults and the associated effect modifiers. Methods: Data for this study were taken from the National Survey of Health and Nutrition in Mexico carried out in 2012. A total of 7986 older adults composed the analytical sample. Cognitive function was assessed using two tests: semantic verbal fluency and three-word memory. The annual concentration of PM 2.5 was calculated using satellite data. Association between exposure to PM 2.5 and cognitive function was estimated using two-level logistic and linear regression models. Results: In adjusted multilevel regression models, each 10 μg/m 3 increase in ambient PM 2.5 raised the odds of a poorer cognitive function using the three-word memory test (OR = 1.37, 95% CI: 1.08, 1.74), and reduced the number of valid animal named in the verbal fluency test (β = −0.72, 95% CI: −1.05, −0.40). Stratified analyses did not yield any significant modification effects of age, sex, indoor pollution, urban/rural dwelling, education, smoking and other factors. Conclusions: This study supports an association between exposure to PM 2.5 concentrations and cognitive function in older adults. This is particularly relevant to low- and middle-income countries, which are marked by a rapid growth of their aging population and high levels of air pollution.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalEnvironment International
Volume117
DOIs
StatePublished - Aug 2018

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income
atmospheric pollution
health and nutrition
aging population
urban pollution
smoking
satellite data
logistics
education
pollution
exposure
animal
test
effect
dwelling
method

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)

Cite this

Salinas-Rodríguez, A., Fernández-Niño, J. A., Manrique-Espinoza, B., Moreno-Banda, G. L., Sosa-Ortiz, A. L., Qian, Z. M., & Lin, H. (2018). Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults Environment International, 117, 1-9. https://doi.org/10.1016/j.envint.2018.04.033
Salinas-Rodríguez, Aarón ; Fernández-Niño, Julián Alfredo ; Manrique-Espinoza, Betty ; Moreno-Banda, Grea Litai ; Sosa-Ortiz, Ana Luisa ; Qian, Zhengmin (Min) ; Lin, Hualiang. / Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults In: Environment International. 2018 ; Vol. 117. pp. 1-9.
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abstract = "Background: Recent epidemiological research has shown that exposure to fine particulate pollution (PM 2.5 ) is associated with a reduction in cognitive function in older adults. However, primary evidence comes from high-income countries, and no specific studies have been conducted in low and middle-income countries where higher air pollution levels exist. Objectives: To estimate the association between the exposure to PM 2.5 and cognitive function in a nationally representative sample of older Mexican adults and the associated effect modifiers. Methods: Data for this study were taken from the National Survey of Health and Nutrition in Mexico carried out in 2012. A total of 7986 older adults composed the analytical sample. Cognitive function was assessed using two tests: semantic verbal fluency and three-word memory. The annual concentration of PM 2.5 was calculated using satellite data. Association between exposure to PM 2.5 and cognitive function was estimated using two-level logistic and linear regression models. Results: In adjusted multilevel regression models, each 10 μg/m 3 increase in ambient PM 2.5 raised the odds of a poorer cognitive function using the three-word memory test (OR = 1.37, 95{\%} CI: 1.08, 1.74), and reduced the number of valid animal named in the verbal fluency test (β = −0.72, 95{\%} CI: −1.05, −0.40). Stratified analyses did not yield any significant modification effects of age, sex, indoor pollution, urban/rural dwelling, education, smoking and other factors. Conclusions: This study supports an association between exposure to PM 2.5 concentrations and cognitive function in older adults. This is particularly relevant to low- and middle-income countries, which are marked by a rapid growth of their aging population and high levels of air pollution.",
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Salinas-Rodríguez, A, Fernández-Niño, JA, Manrique-Espinoza, B, Moreno-Banda, GL, Sosa-Ortiz, AL, Qian, ZM & Lin, H 2018, ' Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults ', Environment International, vol. 117, pp. 1-9. https://doi.org/10.1016/j.envint.2018.04.033

Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults . / Salinas-Rodríguez, Aarón; Fernández-Niño, Julián Alfredo; Manrique-Espinoza, Betty; Moreno-Banda, Grea Litai; Sosa-Ortiz, Ana Luisa; Qian, Zhengmin (Min); Lin, Hualiang.

In: Environment International, Vol. 117, 08.2018, p. 1-9.

Research output: Contribution to journalArticle

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T1 - Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults

AU - Salinas-Rodríguez, Aarón

AU - Fernández-Niño, Julián Alfredo

AU - Manrique-Espinoza, Betty

AU - Moreno-Banda, Grea Litai

AU - Sosa-Ortiz, Ana Luisa

AU - Qian, Zhengmin (Min)

AU - Lin, Hualiang

PY - 2018/8

Y1 - 2018/8

N2 - Background: Recent epidemiological research has shown that exposure to fine particulate pollution (PM 2.5 ) is associated with a reduction in cognitive function in older adults. However, primary evidence comes from high-income countries, and no specific studies have been conducted in low and middle-income countries where higher air pollution levels exist. Objectives: To estimate the association between the exposure to PM 2.5 and cognitive function in a nationally representative sample of older Mexican adults and the associated effect modifiers. Methods: Data for this study were taken from the National Survey of Health and Nutrition in Mexico carried out in 2012. A total of 7986 older adults composed the analytical sample. Cognitive function was assessed using two tests: semantic verbal fluency and three-word memory. The annual concentration of PM 2.5 was calculated using satellite data. Association between exposure to PM 2.5 and cognitive function was estimated using two-level logistic and linear regression models. Results: In adjusted multilevel regression models, each 10 μg/m 3 increase in ambient PM 2.5 raised the odds of a poorer cognitive function using the three-word memory test (OR = 1.37, 95% CI: 1.08, 1.74), and reduced the number of valid animal named in the verbal fluency test (β = −0.72, 95% CI: −1.05, −0.40). Stratified analyses did not yield any significant modification effects of age, sex, indoor pollution, urban/rural dwelling, education, smoking and other factors. Conclusions: This study supports an association between exposure to PM 2.5 concentrations and cognitive function in older adults. This is particularly relevant to low- and middle-income countries, which are marked by a rapid growth of their aging population and high levels of air pollution.

AB - Background: Recent epidemiological research has shown that exposure to fine particulate pollution (PM 2.5 ) is associated with a reduction in cognitive function in older adults. However, primary evidence comes from high-income countries, and no specific studies have been conducted in low and middle-income countries where higher air pollution levels exist. Objectives: To estimate the association between the exposure to PM 2.5 and cognitive function in a nationally representative sample of older Mexican adults and the associated effect modifiers. Methods: Data for this study were taken from the National Survey of Health and Nutrition in Mexico carried out in 2012. A total of 7986 older adults composed the analytical sample. Cognitive function was assessed using two tests: semantic verbal fluency and three-word memory. The annual concentration of PM 2.5 was calculated using satellite data. Association between exposure to PM 2.5 and cognitive function was estimated using two-level logistic and linear regression models. Results: In adjusted multilevel regression models, each 10 μg/m 3 increase in ambient PM 2.5 raised the odds of a poorer cognitive function using the three-word memory test (OR = 1.37, 95% CI: 1.08, 1.74), and reduced the number of valid animal named in the verbal fluency test (β = −0.72, 95% CI: −1.05, −0.40). Stratified analyses did not yield any significant modification effects of age, sex, indoor pollution, urban/rural dwelling, education, smoking and other factors. Conclusions: This study supports an association between exposure to PM 2.5 concentrations and cognitive function in older adults. This is particularly relevant to low- and middle-income countries, which are marked by a rapid growth of their aging population and high levels of air pollution.

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Salinas-Rodríguez A, Fernández-Niño JA, Manrique-Espinoza B, Moreno-Banda GL, Sosa-Ortiz AL, Qian ZM et al. Exposure to ambient PM 2.5 concentrations and cognitive function among older Mexican adults Environment International. 2018 Aug;117:1-9. https://doi.org/10.1016/j.envint.2018.04.033