Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries

Hualiang Lin, Yanfei Guo, Yang Zheng, Xing Zhao, Zheng Cao, Steven E. Rigdon, Hong Xian, Xing Li, Tao Liu, Jianpeng Xiao, Weilin Zeng, Nancy L. Weaver, Zhengmin Qian, Wenjun Ma, Fan Wu

Research output: Contribution to journalArticle

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Abstract

Background Exposure to particulate matter pollution is associated with various cardiopulmonary diseases, which are closely related with disability. The direct relationship between air pollution and disability, however, has not been fully explored. Methods We used data from 45,625 participants in the Study on global AGEing and adult health in six low- and middle-income countries. The 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0) was used to measure the disability with six domains (cognition, mobility, self-care, getting along, life activities, and participation in society). Participants' community addresses were used to estimate annual concentration of PM2.5 using satellite data. We used linear mixed models to examine the effects of PM2.5 on overall and domain-specific WHODAS scores. Results Exposure to PM2.5 was significantly associated with greater disability score (a higher score implies a greater disability); each 10 μg/m3 increase corresponded to 0.72 (95% CI: 0.22, 1.22) increase in overall disability score. Compared with low PM2.5 level (< 14.33 μg/m3), moderate (14.33–27.83 μg/m3) and high exposure levels (> 27.83 μg/m3) were associated with 3.43 (95% CI: 1.43, 5.43) and 3.72 (95% CI: 1.59, 5.86) increase in disability scores. Among the six domains, cognition, mobility and getting along were found to be associated with PM2.5. Stratified analyses found that women and older subjects were more sensitive to this effect. Conclusion Exposure to ambient PM2.5 might be one risk factor of disability in the low- and middle-income countries, women and older adults are the vulnerable population; and among the six domains, cognition, mobility and getting along are more relevant to this effect.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalEnvironment International
Volume104
DOIs
StatePublished - Jan 1 2017

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disability
income
cognition
exposure
World Health Organization
risk factor
particulate matter
satellite data
atmospheric pollution
pollution

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)

Cite this

Lin, Hualiang ; Guo, Yanfei ; Zheng, Yang ; Zhao, Xing ; Cao, Zheng ; Rigdon, Steven E. ; Xian, Hong ; Li, Xing ; Liu, Tao ; Xiao, Jianpeng ; Zeng, Weilin ; Weaver, Nancy L. ; Qian, Zhengmin ; Ma, Wenjun ; Wu, Fan. / Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries. In: Environment International. 2017 ; Vol. 104. pp. 69-75.
@article{b73d6e2da6d841829c703c4ab7a2dddd,
title = "Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries",
abstract = "Background Exposure to particulate matter pollution is associated with various cardiopulmonary diseases, which are closely related with disability. The direct relationship between air pollution and disability, however, has not been fully explored. Methods We used data from 45,625 participants in the Study on global AGEing and adult health in six low- and middle-income countries. The 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0) was used to measure the disability with six domains (cognition, mobility, self-care, getting along, life activities, and participation in society). Participants' community addresses were used to estimate annual concentration of PM2.5 using satellite data. We used linear mixed models to examine the effects of PM2.5 on overall and domain-specific WHODAS scores. Results Exposure to PM2.5 was significantly associated with greater disability score (a higher score implies a greater disability); each 10 μg/m3 increase corresponded to 0.72 (95{\%} CI: 0.22, 1.22) increase in overall disability score. Compared with low PM2.5 level (< 14.33 μg/m3), moderate (14.33–27.83 μg/m3) and high exposure levels (> 27.83 μg/m3) were associated with 3.43 (95{\%} CI: 1.43, 5.43) and 3.72 (95{\%} CI: 1.59, 5.86) increase in disability scores. Among the six domains, cognition, mobility and getting along were found to be associated with PM2.5. Stratified analyses found that women and older subjects were more sensitive to this effect. Conclusion Exposure to ambient PM2.5 might be one risk factor of disability in the low- and middle-income countries, women and older adults are the vulnerable population; and among the six domains, cognition, mobility and getting along are more relevant to this effect.",
author = "Hualiang Lin and Yanfei Guo and Yang Zheng and Xing Zhao and Zheng Cao and Rigdon, {Steven E.} and Hong Xian and Xing Li and Tao Liu and Jianpeng Xiao and Weilin Zeng and Weaver, {Nancy L.} and Zhengmin Qian and Wenjun Ma and Fan Wu",
year = "2017",
month = "1",
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doi = "10.1016/j.envint.2017.04.004",
language = "English (US)",
volume = "104",
pages = "69--75",
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Lin, H, Guo, Y, Zheng, Y, Zhao, X, Cao, Z, Rigdon, SE, Xian, H, Li, X, Liu, T, Xiao, J, Zeng, W, Weaver, NL, Qian, Z, Ma, W & Wu, F 2017, 'Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries', Environment International, vol. 104, pp. 69-75. https://doi.org/10.1016/j.envint.2017.04.004

Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries. / Lin, Hualiang; Guo, Yanfei; Zheng, Yang; Zhao, Xing; Cao, Zheng; Rigdon, Steven E.; Xian, Hong; Li, Xing; Liu, Tao; Xiao, Jianpeng; Zeng, Weilin; Weaver, Nancy L.; Qian, Zhengmin; Ma, Wenjun; Wu, Fan.

In: Environment International, Vol. 104, 01.01.2017, p. 69-75.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Exposure to ambient PM2.5 associated with overall and domain-specific disability among adults in six low- and middle-income countries

AU - Lin, Hualiang

AU - Guo, Yanfei

AU - Zheng, Yang

AU - Zhao, Xing

AU - Cao, Zheng

AU - Rigdon, Steven E.

AU - Xian, Hong

AU - Li, Xing

AU - Liu, Tao

AU - Xiao, Jianpeng

AU - Zeng, Weilin

AU - Weaver, Nancy L.

AU - Qian, Zhengmin

AU - Ma, Wenjun

AU - Wu, Fan

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Background Exposure to particulate matter pollution is associated with various cardiopulmonary diseases, which are closely related with disability. The direct relationship between air pollution and disability, however, has not been fully explored. Methods We used data from 45,625 participants in the Study on global AGEing and adult health in six low- and middle-income countries. The 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0) was used to measure the disability with six domains (cognition, mobility, self-care, getting along, life activities, and participation in society). Participants' community addresses were used to estimate annual concentration of PM2.5 using satellite data. We used linear mixed models to examine the effects of PM2.5 on overall and domain-specific WHODAS scores. Results Exposure to PM2.5 was significantly associated with greater disability score (a higher score implies a greater disability); each 10 μg/m3 increase corresponded to 0.72 (95% CI: 0.22, 1.22) increase in overall disability score. Compared with low PM2.5 level (< 14.33 μg/m3), moderate (14.33–27.83 μg/m3) and high exposure levels (> 27.83 μg/m3) were associated with 3.43 (95% CI: 1.43, 5.43) and 3.72 (95% CI: 1.59, 5.86) increase in disability scores. Among the six domains, cognition, mobility and getting along were found to be associated with PM2.5. Stratified analyses found that women and older subjects were more sensitive to this effect. Conclusion Exposure to ambient PM2.5 might be one risk factor of disability in the low- and middle-income countries, women and older adults are the vulnerable population; and among the six domains, cognition, mobility and getting along are more relevant to this effect.

AB - Background Exposure to particulate matter pollution is associated with various cardiopulmonary diseases, which are closely related with disability. The direct relationship between air pollution and disability, however, has not been fully explored. Methods We used data from 45,625 participants in the Study on global AGEing and adult health in six low- and middle-income countries. The 12-item version of the World Health Organization Disability Assessment Schedule (WHODAS 2.0) was used to measure the disability with six domains (cognition, mobility, self-care, getting along, life activities, and participation in society). Participants' community addresses were used to estimate annual concentration of PM2.5 using satellite data. We used linear mixed models to examine the effects of PM2.5 on overall and domain-specific WHODAS scores. Results Exposure to PM2.5 was significantly associated with greater disability score (a higher score implies a greater disability); each 10 μg/m3 increase corresponded to 0.72 (95% CI: 0.22, 1.22) increase in overall disability score. Compared with low PM2.5 level (< 14.33 μg/m3), moderate (14.33–27.83 μg/m3) and high exposure levels (> 27.83 μg/m3) were associated with 3.43 (95% CI: 1.43, 5.43) and 3.72 (95% CI: 1.59, 5.86) increase in disability scores. Among the six domains, cognition, mobility and getting along were found to be associated with PM2.5. Stratified analyses found that women and older subjects were more sensitive to this effect. Conclusion Exposure to ambient PM2.5 might be one risk factor of disability in the low- and middle-income countries, women and older adults are the vulnerable population; and among the six domains, cognition, mobility and getting along are more relevant to this effect.

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JO - Environmental International

JF - Environmental International

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