Expression of an Orotate Decarboxylating Catalytic Antibody Confers 5-Fluoroorotate Sensitivity to a Pyrimidine Auxotrophic Escherichia coli

An Example of Intracellular Prodrug Activation

Jeffrey A. Smiley, Stephen Benkovic

Research output: Contribution to journalEditorial

14 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)3877-3878
Number of pages2
JournalJournal of the American Chemical Society
Volume117
Issue number13
DOIs
StatePublished - Jan 1 1995

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Catalytic Antibodies
Prodrugs
Escherichia coli
Chemical activation
pyrimidine

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

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title = "Expression of an Orotate Decarboxylating Catalytic Antibody Confers 5-Fluoroorotate Sensitivity to a Pyrimidine Auxotrophic Escherichia coli: An Example of Intracellular Prodrug Activation",
author = "Smiley, {Jeffrey A.} and Stephen Benkovic",
year = "1995",
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language = "English (US)",
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journal = "Journal of the American Chemical Society",
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T2 - An Example of Intracellular Prodrug Activation

AU - Smiley, Jeffrey A.

AU - Benkovic, Stephen

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U2 - 10.1021/ja00118a028

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EP - 3878

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