Extending Pummerer reaction chemistry. Application to the oxidative cyclization of indole derivatives

Ken S. Feldman, Daniela Boneva Vidulova

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Matrix presented. Treatment of 2-(phenylsulfinyl)indoles bearing a pendant nucleophile at C(3) with Tf2O/lutidine triggers a Pummerer-like cyclization to furnish 3,3-spirocyclic-2-(phenylthio)indolenine products, which can, in turn, be hydrolyzed to 3,3-spirocyclic oxindoles.

Original languageEnglish (US)
Pages (from-to)1869-1871
Number of pages3
JournalOrganic Letters
Volume6
Issue number11
DOIs
StatePublished - May 27 2004

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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