Extending pummerer reaction chemistry. Synthesis of (±)- dibromophakellstatin by oxidative cyclization of an imidazole derivative

Ken S. Feldman, Amanda P. Skoumbourdis

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Abstract

(Chemical Equation Presented) The diastereoselective oxidative cyclization of a dihydrooroidin derivative is reported. The thioimidate product formed by application of a new variant of the Pummerer reaction serves as a precursor to dibromophakellstatin.

Original languageEnglish (US)
Pages (from-to)929-931
Number of pages3
JournalOrganic Letters
Volume7
Issue number5
DOIs
Publication statusPublished - Mar 3 2005

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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