Extracellular and intracellular recordings

Research output: Chapter in Book/Report/Conference proceedingChapter


In 1766, Luigi Galvani discovered that electrical activity drove nerve function. His discovery pioneered contemporary electrophysiology, which now consists of extracellular and intracellular approaches used to study electrical signal transfer among neurons. Each approach has advantages/disadvantages and useful applications that once understood can greatly benefit an experimenter looking to design the appropriate experiments. The purpose of this chapter is to provide the reader with core understanding for each approach focusing on in vitro applications (in vivo electrophysiology is covered in Chap. 22)

Original languageEnglish (US)
Title of host publicationNeuromethods
PublisherHumana Press Inc.
Number of pages13
StatePublished - Oct 1 2016

Publication series

ISSN (Print)0893-2336
ISSN (Electronic)1940-6045

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Psychiatry and Mental health


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