Extracellular recordings

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The common approach to scientific research is to follow the theory of reductionism, which dissects complex scientific questions into basic components, thus limiting experimental variables and potential confounds in the experimental results. In electrophysiology, the reductionist’s approach has successfully provided a plethora of groundbreaking findings especially through the use of ex vivo measurements whereby the experimenter can more easily manipulate the circuit and/or neuron. However, by taking this ex vivo approach, many additional findings may go undiscovered and the physiological relevance may be questioned as neurons or circuits are removed from their in vivo milieu. Therefore, in vivo electrophysiology is a useful tool for the beginning electrophysiologist to become acquainted with as it extends ex vivo findings into physiologically relevant discoveries.

Original languageEnglish (US)
Title of host publicationNeuromethods
PublisherHumana Press Inc.
Pages249-257
Number of pages9
DOIs
StatePublished - Jan 1 2015

Publication series

NameNeuromethods
Volume112
ISSN (Print)0893-2336
ISSN (Electronic)1940-6045

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Psychiatry and Mental health

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  • Cite this

    Graziane, N., & Dong, Y. (2015). Extracellular recordings. In Neuromethods (pp. 249-257). (Neuromethods; Vol. 112). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-3274-0_22