Facile synthesis of @-tide β-strand peptidomimetics: Improved assembly in solution and on solid phase

Scott T. Phillips; Giovanni Piersanti; Matthias Rüth; Niko Gubernator; Bettina Van Lengerich; Paul A. Bartlett

doi:10.1021/ol048262j

Facile synthesis of @-tide β-strand peptidomimetics: Improved assembly in solution and on solid phase

Scott T. Phillips, Giovanni Piersanti, Matthias Rüth, Niko Gubernator, Bettina Van Lengerich, Paul A. Bartlett

Chemistry

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16 Citations (SciVal)

Abstract

(Chemical equation presented) The synthesis of @-tide β-strand peptidomimetics has been improved such that oligomers now can be obtained from solution- and solid-phase synthesis protocols approaching the efficiency and flexibility of peptide chemistry. These methods enable the synthesis of @-tide oligomers with a variety of amino acids and with lengths up to 13 units.

Original language	English (US)
Pages (from-to)	4483-4485
Number of pages	3
Journal	Organic Letters
Volume	6
Issue number	24
DOIs	https://doi.org/10.1021/ol048262j
State	Published - Nov 25 2004

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol048262j

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abstract = "(Chemical equation presented) The synthesis of @-tide β-strand peptidomimetics has been improved such that oligomers now can be obtained from solution- and solid-phase synthesis protocols approaching the efficiency and flexibility of peptide chemistry. These methods enable the synthesis of @-tide oligomers with a variety of amino acids and with lengths up to 13 units.",

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T2 - Improved assembly in solution and on solid phase

AU - Phillips, Scott T.

AU - Piersanti, Giovanni

AU - Rüth, Matthias

AU - Gubernator, Niko

AU - Van Lengerich, Bettina

AU - Bartlett, Paul A.

PY - 2004/11/25

Y1 - 2004/11/25

N2 - (Chemical equation presented) The synthesis of @-tide β-strand peptidomimetics has been improved such that oligomers now can be obtained from solution- and solid-phase synthesis protocols approaching the efficiency and flexibility of peptide chemistry. These methods enable the synthesis of @-tide oligomers with a variety of amino acids and with lengths up to 13 units.

AB - (Chemical equation presented) The synthesis of @-tide β-strand peptidomimetics has been improved such that oligomers now can be obtained from solution- and solid-phase synthesis protocols approaching the efficiency and flexibility of peptide chemistry. These methods enable the synthesis of @-tide oligomers with a variety of amino acids and with lengths up to 13 units.

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ER -

Facile synthesis of @-tide β-strand peptidomimetics: Improved assembly in solution and on solid phase

Abstract

All Science Journal Classification (ASJC) codes

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