False-positive bone metastases on PET/CT secondary to sarcoidosis in a patient with rectal cancer

Kenneth M. Montini, Mark Tulchinsky

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Patient with newly diagnosed rectal cancer underwent staging PET/CT that showed an intensely [F-18]-fluoro-2-deoxy-D-glucose (FDG)-avid rectal tumor, but also multifocal, intensely FDG-avid mediastinal lymphadenopathy and skeletal foci. The bone foci had no corresponding lytic or blastic lesions on CT. There were mildly FDG-avid reticulonodular opacities in both lungs. This apparent metastatic distribution pattern was highly atypical for rectal cancer; therefore, biopsy was recommended. It showed granulomatous disease in a lymph node and the bone marrow, indicating sarcoidosis. Bone involvement in sarcoidosis is rare, but can lead to the false-positive appearance of metastatic disease on PET/CT.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalClinical nuclear medicine
Volume37
Issue number3
DOIs
StatePublished - Mar 1 2012

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Deoxyglucose
Sarcoidosis
Rectal Neoplasms
Neoplasm Metastasis
Bone and Bones
Neoplasm Staging
Lymph Nodes
Bone Marrow
Biopsy
Lung

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

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False-positive bone metastases on PET/CT secondary to sarcoidosis in a patient with rectal cancer. / Montini, Kenneth M.; Tulchinsky, Mark.

In: Clinical nuclear medicine, Vol. 37, No. 3, 01.03.2012, p. 307-310.

Research output: Contribution to journalArticle

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