Fatigue and cytokines

Christine A. Gallati, Howard S. Smith

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Fatigue remains an incompletely understood but extremely common symptom that mat be very challenging and difficult to address. One potential class of mediators that may contribute to fatigue, especially in inflammatory states are cytokines. Cytokines are small endogenous hydrophilic proteins and glycoproteins which may be involved in cellto- cell communication and/or signaling pathways that could contribute to the genesis and/or maintenance of fatigue. It is difficult to find robust evidence for specific cytokines directly resulting in the sensation of fatigue, however it appears that in some circumstances cytokines may be involved in contributing to fatigue. A greater understanding of which cytokines in which medical conditions/states may be involved in contributing to fatigue, may help clinicians to optimally address this potentially debilitating symptom.

Original languageEnglish (US)
Title of host publicationHandbook of Fatigue in Health and Disease
PublisherNova Science Publishers, Inc.
Pages33-49
Number of pages17
ISBN (Electronic)9781621001720
ISBN (Print)9781617619205
StatePublished - Jan 1 2011

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Fatigue
Cytokines
Cell Communication
Glycoproteins
Maintenance
Proteins

All Science Journal Classification (ASJC) codes

  • Health Professions(all)
  • Medicine(all)

Cite this

Gallati, C. A., & Smith, H. S. (2011). Fatigue and cytokines. In Handbook of Fatigue in Health and Disease (pp. 33-49). Nova Science Publishers, Inc..
Gallati, Christine A. ; Smith, Howard S. / Fatigue and cytokines. Handbook of Fatigue in Health and Disease. Nova Science Publishers, Inc., 2011. pp. 33-49
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Gallati, CA & Smith, HS 2011, Fatigue and cytokines. in Handbook of Fatigue in Health and Disease. Nova Science Publishers, Inc., pp. 33-49.

Fatigue and cytokines. / Gallati, Christine A.; Smith, Howard S.

Handbook of Fatigue in Health and Disease. Nova Science Publishers, Inc., 2011. p. 33-49.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Gallati CA, Smith HS. Fatigue and cytokines. In Handbook of Fatigue in Health and Disease. Nova Science Publishers, Inc. 2011. p. 33-49