Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment

Jingyun Wang, Jing Jin, Ayesha Malik, Ruth Shoge, Siva Meiyeppen, Yi Pang, Kelly Yin, Megan Allen, Brandy Scombordi, Ajay Soni, Daniel E. Neely, Kai Januschowski

Research output: Contribution to journalArticle

Abstract

Background: Liquid crystal glasses use an intermittent occlusion technique and may improve compliance compared to adhesive patches. Previous studies support the effectiveness of intermittent occlusion therapy (IO therapy) glasses for amblyopia treatment. However, objective compliance for these glasses has not been measured. The purpose of this study was to investigate the feasibility of using a microsensor to monitor objective compliance with IO therapy glasses. Methods: Children 3 to ≤8 years of age with unilateral amblyopia were enrolled. All subjects had optimal refractive correction (if needed) for at least 5 weeks without improvement. Subjects were prescribed IO therapy glasses, set at 30-second opaque/transparent intervals (ie, occluded 50% of wear time). Wear time was prescribed according to amblyopia severity. For each patient, objective compliance with the IO therapy glasses was monitored by means of a microsensor. Results: A total of 13 subjects returned with microsensor data. Compliance varied among and within individuals. General compliance averaged 51.6% (range, 10%-97%). Mean daily compliance decreased slightly over time. On average, patients' visual acuity improved 0.14 ± 0.15 logMAR (range, −0.1 to 0.5 logMAR). No parents reported that their child had social concerns related to the attached microsensor. Conclusions: Objective compliance with IO therapy glasses can be monitored by a simple microsensor reliably. In our study cohort, objective compliance with IO therapy glasses varied among individuals, but on average it declined slightly over time.

Original languageEnglish (US)
Pages (from-to)205.e1-205.e5
JournalJournal of AAPOS
Volume23
Issue number4
DOIs
StatePublished - Aug 1 2019

Fingerprint

Amblyopia
Glass
Compliance
Therapeutics
Patient Acuity
Liquid Crystals
Adhesives
Visual Acuity
Cohort Studies
Parents

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology

Cite this

Wang, J., Jin, J., Malik, A., Shoge, R., Meiyeppen, S., Pang, Y., ... Januschowski, K. (2019). Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment. Journal of AAPOS, 23(4), 205.e1-205.e5. https://doi.org/10.1016/j.jaapos.2019.04.009
Wang, Jingyun ; Jin, Jing ; Malik, Ayesha ; Shoge, Ruth ; Meiyeppen, Siva ; Pang, Yi ; Yin, Kelly ; Allen, Megan ; Scombordi, Brandy ; Soni, Ajay ; Neely, Daniel E. ; Januschowski, Kai. / Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment. In: Journal of AAPOS. 2019 ; Vol. 23, No. 4. pp. 205.e1-205.e5.
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abstract = "Background: Liquid crystal glasses use an intermittent occlusion technique and may improve compliance compared to adhesive patches. Previous studies support the effectiveness of intermittent occlusion therapy (IO therapy) glasses for amblyopia treatment. However, objective compliance for these glasses has not been measured. The purpose of this study was to investigate the feasibility of using a microsensor to monitor objective compliance with IO therapy glasses. Methods: Children 3 to ≤8 years of age with unilateral amblyopia were enrolled. All subjects had optimal refractive correction (if needed) for at least 5 weeks without improvement. Subjects were prescribed IO therapy glasses, set at 30-second opaque/transparent intervals (ie, occluded 50{\%} of wear time). Wear time was prescribed according to amblyopia severity. For each patient, objective compliance with the IO therapy glasses was monitored by means of a microsensor. Results: A total of 13 subjects returned with microsensor data. Compliance varied among and within individuals. General compliance averaged 51.6{\%} (range, 10{\%}-97{\%}). Mean daily compliance decreased slightly over time. On average, patients' visual acuity improved 0.14 ± 0.15 logMAR (range, −0.1 to 0.5 logMAR). No parents reported that their child had social concerns related to the attached microsensor. Conclusions: Objective compliance with IO therapy glasses can be monitored by a simple microsensor reliably. In our study cohort, objective compliance with IO therapy glasses varied among individuals, but on average it declined slightly over time.",
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Wang, J, Jin, J, Malik, A, Shoge, R, Meiyeppen, S, Pang, Y, Yin, K, Allen, M, Scombordi, B, Soni, A, Neely, DE & Januschowski, K 2019, 'Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment', Journal of AAPOS, vol. 23, no. 4, pp. 205.e1-205.e5. https://doi.org/10.1016/j.jaapos.2019.04.009

Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment. / Wang, Jingyun; Jin, Jing; Malik, Ayesha; Shoge, Ruth; Meiyeppen, Siva; Pang, Yi; Yin, Kelly; Allen, Megan; Scombordi, Brandy; Soni, Ajay; Neely, Daniel E.; Januschowski, Kai.

In: Journal of AAPOS, Vol. 23, No. 4, 01.08.2019, p. 205.e1-205.e5.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment

AU - Wang, Jingyun

AU - Jin, Jing

AU - Malik, Ayesha

AU - Shoge, Ruth

AU - Meiyeppen, Siva

AU - Pang, Yi

AU - Yin, Kelly

AU - Allen, Megan

AU - Scombordi, Brandy

AU - Soni, Ajay

AU - Neely, Daniel E.

AU - Januschowski, Kai

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Background: Liquid crystal glasses use an intermittent occlusion technique and may improve compliance compared to adhesive patches. Previous studies support the effectiveness of intermittent occlusion therapy (IO therapy) glasses for amblyopia treatment. However, objective compliance for these glasses has not been measured. The purpose of this study was to investigate the feasibility of using a microsensor to monitor objective compliance with IO therapy glasses. Methods: Children 3 to ≤8 years of age with unilateral amblyopia were enrolled. All subjects had optimal refractive correction (if needed) for at least 5 weeks without improvement. Subjects were prescribed IO therapy glasses, set at 30-second opaque/transparent intervals (ie, occluded 50% of wear time). Wear time was prescribed according to amblyopia severity. For each patient, objective compliance with the IO therapy glasses was monitored by means of a microsensor. Results: A total of 13 subjects returned with microsensor data. Compliance varied among and within individuals. General compliance averaged 51.6% (range, 10%-97%). Mean daily compliance decreased slightly over time. On average, patients' visual acuity improved 0.14 ± 0.15 logMAR (range, −0.1 to 0.5 logMAR). No parents reported that their child had social concerns related to the attached microsensor. Conclusions: Objective compliance with IO therapy glasses can be monitored by a simple microsensor reliably. In our study cohort, objective compliance with IO therapy glasses varied among individuals, but on average it declined slightly over time.

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