Feasibility of real-time intraoperative fluorescence imaging of dural sinus thrombosis

Laureen D. Hachem, Seyed Alireza Mansouri, Joseph Chen, Farhad Pirouzmand

Research output: Contribution to journalArticle

Abstract

Dural sinus thrombosis is a well-recognized and potentially serious complication following lateral skull base surgery. Methods of diagnosis are limited to post-operative computerized tomography scans or magnetic resonance venography. There are currently no reports of an intraoperative technique used to detect dural sinus thrombosis. Here, we describe the case of a 62-year-old woman who underwent translabyrinthine resection of a right vestibular schwannoma with no evidence of sinus thrombosis on pre-operative scans. Following tumor resection, patency of the sigmoid sinus was assessed intraoperatively using indocyanine green (ICG) videography which revealed a lack of flow in the right sigmoid sinus. Postoperative CT scan confirmed thrombosis of the right sigmoid sinus. We present the first report of real-time intraoperative diagnosis of sigmoid sinus thrombosis during removal of a vestibular schwannoma. ICG videography may be used for intraoperative visualization of dural sinus integrity and patency during prolonged or technically challenging microsurgical procedures. This technique may enable periodic monitoring and early identification of filling defects which can guide further intraoperative strategies and postoperative monitoring.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalJournal of Clinical Neuroscience
Volume52
DOIs
StatePublished - Jun 1 2018

Fingerprint

Intracranial Sinus Thrombosis
Optical Imaging
Sigmoid Colon
Indocyanine Green
Acoustic Neuroma
Phlebography
Skull Base
Thrombosis
Magnetic Resonance Spectroscopy
Tomography
Neoplasms

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

@article{4754fa18760f4e108c2ef7342d4ca46a,
title = "Feasibility of real-time intraoperative fluorescence imaging of dural sinus thrombosis",
abstract = "Dural sinus thrombosis is a well-recognized and potentially serious complication following lateral skull base surgery. Methods of diagnosis are limited to post-operative computerized tomography scans or magnetic resonance venography. There are currently no reports of an intraoperative technique used to detect dural sinus thrombosis. Here, we describe the case of a 62-year-old woman who underwent translabyrinthine resection of a right vestibular schwannoma with no evidence of sinus thrombosis on pre-operative scans. Following tumor resection, patency of the sigmoid sinus was assessed intraoperatively using indocyanine green (ICG) videography which revealed a lack of flow in the right sigmoid sinus. Postoperative CT scan confirmed thrombosis of the right sigmoid sinus. We present the first report of real-time intraoperative diagnosis of sigmoid sinus thrombosis during removal of a vestibular schwannoma. ICG videography may be used for intraoperative visualization of dural sinus integrity and patency during prolonged or technically challenging microsurgical procedures. This technique may enable periodic monitoring and early identification of filling defects which can guide further intraoperative strategies and postoperative monitoring.",
author = "Hachem, {Laureen D.} and Mansouri, {Seyed Alireza} and Joseph Chen and Farhad Pirouzmand",
year = "2018",
month = "6",
day = "1",
doi = "10.1016/j.jocn.2018.03.011",
language = "English (US)",
volume = "52",
pages = "153--155",
journal = "Journal of Clinical Neuroscience",
issn = "0967-5868",
publisher = "Churchill Livingstone",

}

Feasibility of real-time intraoperative fluorescence imaging of dural sinus thrombosis. / Hachem, Laureen D.; Mansouri, Seyed Alireza; Chen, Joseph; Pirouzmand, Farhad.

In: Journal of Clinical Neuroscience, Vol. 52, 01.06.2018, p. 153-155.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Feasibility of real-time intraoperative fluorescence imaging of dural sinus thrombosis

AU - Hachem, Laureen D.

AU - Mansouri, Seyed Alireza

AU - Chen, Joseph

AU - Pirouzmand, Farhad

PY - 2018/6/1

Y1 - 2018/6/1

N2 - Dural sinus thrombosis is a well-recognized and potentially serious complication following lateral skull base surgery. Methods of diagnosis are limited to post-operative computerized tomography scans or magnetic resonance venography. There are currently no reports of an intraoperative technique used to detect dural sinus thrombosis. Here, we describe the case of a 62-year-old woman who underwent translabyrinthine resection of a right vestibular schwannoma with no evidence of sinus thrombosis on pre-operative scans. Following tumor resection, patency of the sigmoid sinus was assessed intraoperatively using indocyanine green (ICG) videography which revealed a lack of flow in the right sigmoid sinus. Postoperative CT scan confirmed thrombosis of the right sigmoid sinus. We present the first report of real-time intraoperative diagnosis of sigmoid sinus thrombosis during removal of a vestibular schwannoma. ICG videography may be used for intraoperative visualization of dural sinus integrity and patency during prolonged or technically challenging microsurgical procedures. This technique may enable periodic monitoring and early identification of filling defects which can guide further intraoperative strategies and postoperative monitoring.

AB - Dural sinus thrombosis is a well-recognized and potentially serious complication following lateral skull base surgery. Methods of diagnosis are limited to post-operative computerized tomography scans or magnetic resonance venography. There are currently no reports of an intraoperative technique used to detect dural sinus thrombosis. Here, we describe the case of a 62-year-old woman who underwent translabyrinthine resection of a right vestibular schwannoma with no evidence of sinus thrombosis on pre-operative scans. Following tumor resection, patency of the sigmoid sinus was assessed intraoperatively using indocyanine green (ICG) videography which revealed a lack of flow in the right sigmoid sinus. Postoperative CT scan confirmed thrombosis of the right sigmoid sinus. We present the first report of real-time intraoperative diagnosis of sigmoid sinus thrombosis during removal of a vestibular schwannoma. ICG videography may be used for intraoperative visualization of dural sinus integrity and patency during prolonged or technically challenging microsurgical procedures. This technique may enable periodic monitoring and early identification of filling defects which can guide further intraoperative strategies and postoperative monitoring.

UR - http://www.scopus.com/inward/record.url?scp=85045111782&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045111782&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2018.03.011

DO - 10.1016/j.jocn.2018.03.011

M3 - Article

C2 - 29650453

AN - SCOPUS:85045111782

VL - 52

SP - 153

EP - 155

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

SN - 0967-5868

ER -