Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy: Cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules

Ayesha N. Khalid, Sadeq A. Quraishi, Christopher S. Hollenbeak, Brendan C. Stack

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Background. Ultrasound-guided fine-needle aspiration biopsy (ultrasound-guided FNAB) is considered the diagnostic test of choice when a fine-needle aspiration biopsy (FNAB) returns an inconclusive diagnosis because of cytologic ambiguity or paucity of specimen. Methods. Cost-effectiveness analysis utilizing a decision tree was used to model the diagnostic strategies. The decision analysis model was parameterized using costs from a large, academic medical center and probabilities from existing literature. Outcomes included the incremental cost per additional case correctly diagnosed. Results. All data are reported as frontline ultrasound-guided FNAB strategy versus FNAB strategy - expected cost: $1329 versus $1312; expected number of cases correctly diagnosed (per 1000 biopsies): 980 versus 920; incremental cost per additional correctly diagnosed case: $289. Conclusion. The use of ultrasound-guided FNAB as the initial modality for tissue biopsy of a thyroid nodule is more effective than traditional FNAB at an additional cost of $289 per additional correct diagnosis.

Original languageEnglish (US)
Pages (from-to)1035-1039
Number of pages5
JournalHead and Neck
Volume30
Issue number8
DOIs
StatePublished - Aug 1 2008

Fingerprint

Thyroid Nodule
Fine Needle Biopsy
Cost-Benefit Analysis
Costs and Cost Analysis
Biopsy
Decision Trees
Decision Support Techniques
Routine Diagnostic Tests

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

@article{89cb6069c4804dd285f2b2ff4bdcec4b,
title = "Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy: Cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules",
abstract = "Background. Ultrasound-guided fine-needle aspiration biopsy (ultrasound-guided FNAB) is considered the diagnostic test of choice when a fine-needle aspiration biopsy (FNAB) returns an inconclusive diagnosis because of cytologic ambiguity or paucity of specimen. Methods. Cost-effectiveness analysis utilizing a decision tree was used to model the diagnostic strategies. The decision analysis model was parameterized using costs from a large, academic medical center and probabilities from existing literature. Outcomes included the incremental cost per additional case correctly diagnosed. Results. All data are reported as frontline ultrasound-guided FNAB strategy versus FNAB strategy - expected cost: $1329 versus $1312; expected number of cases correctly diagnosed (per 1000 biopsies): 980 versus 920; incremental cost per additional correctly diagnosed case: $289. Conclusion. The use of ultrasound-guided FNAB as the initial modality for tissue biopsy of a thyroid nodule is more effective than traditional FNAB at an additional cost of $289 per additional correct diagnosis.",
author = "Khalid, {Ayesha N.} and Quraishi, {Sadeq A.} and Hollenbeak, {Christopher S.} and Stack, {Brendan C.}",
year = "2008",
month = "8",
day = "1",
doi = "10.1002/hed.20829",
language = "English (US)",
volume = "30",
pages = "1035--1039",
journal = "Head and Neck",
issn = "1043-3074",
publisher = "John Wiley and Sons Inc.",
number = "8",

}

Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy : Cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules. / Khalid, Ayesha N.; Quraishi, Sadeq A.; Hollenbeak, Christopher S.; Stack, Brendan C.

In: Head and Neck, Vol. 30, No. 8, 01.08.2008, p. 1035-1039.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fine-needle aspiration biopsy versus ultrasound-guided fine-needle aspiration biopsy

T2 - Cost-effectiveness as a frontline diagnostic modality for solitary thyroid nodules

AU - Khalid, Ayesha N.

AU - Quraishi, Sadeq A.

AU - Hollenbeak, Christopher S.

AU - Stack, Brendan C.

PY - 2008/8/1

Y1 - 2008/8/1

N2 - Background. Ultrasound-guided fine-needle aspiration biopsy (ultrasound-guided FNAB) is considered the diagnostic test of choice when a fine-needle aspiration biopsy (FNAB) returns an inconclusive diagnosis because of cytologic ambiguity or paucity of specimen. Methods. Cost-effectiveness analysis utilizing a decision tree was used to model the diagnostic strategies. The decision analysis model was parameterized using costs from a large, academic medical center and probabilities from existing literature. Outcomes included the incremental cost per additional case correctly diagnosed. Results. All data are reported as frontline ultrasound-guided FNAB strategy versus FNAB strategy - expected cost: $1329 versus $1312; expected number of cases correctly diagnosed (per 1000 biopsies): 980 versus 920; incremental cost per additional correctly diagnosed case: $289. Conclusion. The use of ultrasound-guided FNAB as the initial modality for tissue biopsy of a thyroid nodule is more effective than traditional FNAB at an additional cost of $289 per additional correct diagnosis.

AB - Background. Ultrasound-guided fine-needle aspiration biopsy (ultrasound-guided FNAB) is considered the diagnostic test of choice when a fine-needle aspiration biopsy (FNAB) returns an inconclusive diagnosis because of cytologic ambiguity or paucity of specimen. Methods. Cost-effectiveness analysis utilizing a decision tree was used to model the diagnostic strategies. The decision analysis model was parameterized using costs from a large, academic medical center and probabilities from existing literature. Outcomes included the incremental cost per additional case correctly diagnosed. Results. All data are reported as frontline ultrasound-guided FNAB strategy versus FNAB strategy - expected cost: $1329 versus $1312; expected number of cases correctly diagnosed (per 1000 biopsies): 980 versus 920; incremental cost per additional correctly diagnosed case: $289. Conclusion. The use of ultrasound-guided FNAB as the initial modality for tissue biopsy of a thyroid nodule is more effective than traditional FNAB at an additional cost of $289 per additional correct diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=50249170314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=50249170314&partnerID=8YFLogxK

U2 - 10.1002/hed.20829

DO - 10.1002/hed.20829

M3 - Article

C2 - 18442056

AN - SCOPUS:50249170314

VL - 30

SP - 1035

EP - 1039

JO - Head and Neck

JF - Head and Neck

SN - 1043-3074

IS - 8

ER -