First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

Emmi I.T. Helle, Preston Biegley, Joshua W. Knowles, Joseph B. Leader, Sarah Pendergrass, Wei Yang, Gerald R. Reaven, Gary M. Shaw, Marylyn Ritchie, James R. Priest

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In a retrospective study of 19 171 mother-child dyads, elevated random plasma glucose values during early pregnancy were directly correlated with increased risk for congenital heart disease in offspring. Plasma glucose levels proximal to the period of cardiac development may represent a modifiable risk factor for congenital heart disease in expectant mothers without diabetes.

Original languageEnglish (US)
Pages (from-to)275-278
Number of pages4
JournalJournal of Pediatrics
Volume195
DOIs
StatePublished - Apr 2018

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First Pregnancy Trimester
Heart Diseases
Mothers
Glucose
Retrospective Studies
Pregnancy

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Cite this

Helle, E. I. T., Biegley, P., Knowles, J. W., Leader, J. B., Pendergrass, S., Yang, W., ... Priest, J. R. (2018). First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring. Journal of Pediatrics, 195, 275-278. https://doi.org/10.1016/j.jpeds.2017.10.046
Helle, Emmi I.T. ; Biegley, Preston ; Knowles, Joshua W. ; Leader, Joseph B. ; Pendergrass, Sarah ; Yang, Wei ; Reaven, Gerald R. ; Shaw, Gary M. ; Ritchie, Marylyn ; Priest, James R. / First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring. In: Journal of Pediatrics. 2018 ; Vol. 195. pp. 275-278.
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Helle, EIT, Biegley, P, Knowles, JW, Leader, JB, Pendergrass, S, Yang, W, Reaven, GR, Shaw, GM, Ritchie, M & Priest, JR 2018, 'First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring', Journal of Pediatrics, vol. 195, pp. 275-278. https://doi.org/10.1016/j.jpeds.2017.10.046

First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring. / Helle, Emmi I.T.; Biegley, Preston; Knowles, Joshua W.; Leader, Joseph B.; Pendergrass, Sarah; Yang, Wei; Reaven, Gerald R.; Shaw, Gary M.; Ritchie, Marylyn; Priest, James R.

In: Journal of Pediatrics, Vol. 195, 04.2018, p. 275-278.

Research output: Contribution to journalArticle

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