First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

Emmi I.T. Helle, Preston Biegley, Joshua W. Knowles, Joseph B. Leader, Sarah Pendergrass, Wei Yang, Gerald R. Reaven, Gary M. Shaw, Marylyn Ritchie, James R. Priest

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

In a retrospective study of 19 171 mother-child dyads, elevated random plasma glucose values during early pregnancy were directly correlated with increased risk for congenital heart disease in offspring. Plasma glucose levels proximal to the period of cardiac development may represent a modifiable risk factor for congenital heart disease in expectant mothers without diabetes.

Original languageEnglish (US)
Pages (from-to)275-278
Number of pages4
JournalJournal of Pediatrics
Volume195
DOIs
StatePublished - Apr 2018

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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