Abstract
Recent studies have demonstrated the importance of flavonoid intake and disease risk, however the association between flavonoid intake and obesity has not been evaluated in a nationally representative sample of US adults. The objective of the study was to evaluate the association between flavonoid consumption and established risk factors for obesity and obesity-related inflammation. Data from a nationally representative sample of 9551 adults who participated in the 2005-2008 National Health and Nutrition Examination Survey (NHANES) were analyzed. Flavonoid consumption was inversely associated with obesity in both men and women in multivariate models. Adults in the highest quartile of flavonoid intake had significantly lower body mass index and waist circumference than those in the lowest quartile of flavonoid intake (P<0.03 and P<0.04, respectively), and flavonoid intake was inversely related to C-reactive protein levels in women (p-trend, 0.01). These findings support a growing body of laboratory evidence that flavonoid consumption may be beneficial for disease prevention.
| Original language | English (US) |
|---|---|
| Article number | e276 |
| Journal | Nutrition and Diabetes |
| Volume | 7 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 15 2017 |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
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Flavonoid intake is inversely associated with obesity and C-reactive protein, a marker for inflammation, in US adults. / Vernarelli, J. A.; Lambert, J. D.
In: Nutrition and Diabetes, Vol. 7, No. 5, e276, 15.05.2017.Research output: Contribution to journal › Article
TY - JOUR
T1 - Flavonoid intake is inversely associated with obesity and C-reactive protein, a marker for inflammation, in US adults
AU - Vernarelli, J. A.
AU - Lambert, J. D.
PY - 2017/5/15
Y1 - 2017/5/15
N2 - Recent studies have demonstrated the importance of flavonoid intake and disease risk, however the association between flavonoid intake and obesity has not been evaluated in a nationally representative sample of US adults. The objective of the study was to evaluate the association between flavonoid consumption and established risk factors for obesity and obesity-related inflammation. Data from a nationally representative sample of 9551 adults who participated in the 2005-2008 National Health and Nutrition Examination Survey (NHANES) were analyzed. Flavonoid consumption was inversely associated with obesity in both men and women in multivariate models. Adults in the highest quartile of flavonoid intake had significantly lower body mass index and waist circumference than those in the lowest quartile of flavonoid intake (P<0.03 and P<0.04, respectively), and flavonoid intake was inversely related to C-reactive protein levels in women (p-trend, 0.01). These findings support a growing body of laboratory evidence that flavonoid consumption may be beneficial for disease prevention.
AB - Recent studies have demonstrated the importance of flavonoid intake and disease risk, however the association between flavonoid intake and obesity has not been evaluated in a nationally representative sample of US adults. The objective of the study was to evaluate the association between flavonoid consumption and established risk factors for obesity and obesity-related inflammation. Data from a nationally representative sample of 9551 adults who participated in the 2005-2008 National Health and Nutrition Examination Survey (NHANES) were analyzed. Flavonoid consumption was inversely associated with obesity in both men and women in multivariate models. Adults in the highest quartile of flavonoid intake had significantly lower body mass index and waist circumference than those in the lowest quartile of flavonoid intake (P<0.03 and P<0.04, respectively), and flavonoid intake was inversely related to C-reactive protein levels in women (p-trend, 0.01). These findings support a growing body of laboratory evidence that flavonoid consumption may be beneficial for disease prevention.
UR - http://www.scopus.com/inward/record.url?scp=85019629292&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019629292&partnerID=8YFLogxK
U2 - 10.1038/nutd.2017.22
DO - 10.1038/nutd.2017.22
M3 - Article
C2 - 28504712
AN - SCOPUS:85019629292
VL - 7
JO - Nutrition and Diabetes
JF - Nutrition and Diabetes
SN - 2044-4052
IS - 5
M1 - e276
ER -