Food Plant Derived Disease Tolerance And Resistance In A Natural Butterfly-Plant-Parasite Interactions

Eleanore D. Sternberg, Thierry Lefèvre, James Li, Carlos Lopez Fernandez de Castillejo, Hui Li, Mark D. Hunter, Jacobus C. de Roode

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Organisms can protect themselves against parasite-induced fitness costs through resistance or tolerance. Resistance includes mechanisms that prevent infection or limit parasite growth while tolerance alleviates the fitness costs from parasitism without limiting infection. Although tolerance and resistance affect host-parasite coevolution in fundamentally different ways, tolerance has often been ignored in animal-parasite systems. Where it has been studied, tolerance has been assumed to be a genetic mechanism, unaffected by the host environment. Here we studied the effects of host ecology on tolerance and resistance to infection by rearing monarch butterflies on 12 different species of milkweed food plants and infecting them with a naturally occurring protozoan parasite. Our results show that monarch butterflies experience different levels of tolerance to parasitism depending on the species of milkweed that they feed on, with some species providing over twofold greater tolerance than other milkweed species. Resistance was also affected by milkweed species, but there was no relationship between milkweed-conferred resistance and tolerance. Chemical analysis suggests that infected monarchs obtain highest fitness when reared on milkweeds with an intermediate concentration, diversity, and polarity of toxic secondary plant chemicals known as cardenolides. Our results demonstrate that environmental factors-such as interacting species in ecological food webs-are important drivers of disease tolerance.

Original languageEnglish (US)
Pages (from-to)3367-3376
Number of pages10
JournalEvolution
Volume66
Issue number11
DOIs
StatePublished - Nov 1 2012

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Agricultural and Biological Sciences(all)

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    Sternberg, E. D., Lefèvre, T., Li, J., de Castillejo, C. L. F., Li, H., Hunter, M. D., & de Roode, J. C. (2012). Food Plant Derived Disease Tolerance And Resistance In A Natural Butterfly-Plant-Parasite Interactions. Evolution, 66(11), 3367-3376. https://doi.org/10.1111/j.1558-5646.2012.01693.x