FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

B. Tracy Nixon, Richard J. Wang

Research output: Contribution to journalEditorial

44 Citations (Scopus)

Abstract

Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

Original languageEnglish (US)
Pages (from-to)589-593
Number of pages5
JournalPhotochemistry and Photobiology
Volume26
Issue number6
DOIs
StatePublished - Dec 1977

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riboflavin
Riboflavin
Bilirubin
Cell culture
tyrosine
tryptophan
Cell Culture Techniques
Tryptophan
Cells
Tyrosine
Light
Irradiation
Tissue culture
culture media
Fluorescent lamps
Eagles
irradiation
Poisons
luminaires
Culture Media

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry

Cite this

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title = "FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT",
abstract = "Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.",
author = "Nixon, {B. Tracy} and Wang, {Richard J.}",
year = "1977",
month = "12",
doi = "10.1111/j.1751-1097.1977.tb07537.x",
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journal = "Photochemistry and Photobiology",
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}

FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT. / Nixon, B. Tracy; Wang, Richard J.

In: Photochemistry and Photobiology, Vol. 26, No. 6, 12.1977, p. 589-593.

Research output: Contribution to journalEditorial

TY - JOUR

T1 - FORMATION OF PHOTOPRODUCTS LETHAL FOR HUMAN CELLS IN CULTURE BY DAYLIGHT FLUORESCENT LIGHT AND BILIRUBIN LIGHT

AU - Nixon, B. Tracy

AU - Wang, Richard J.

PY - 1977/12

Y1 - 1977/12

N2 - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

AB - Abstract. Irradiation of Dulbecco's modified Eagle's tissue culture medium with “Daylight,”“Special Blue,” or “Bilirubin” fluorescent light produces photoproducts lethal to human cells. Killing is abolished when (1) riboflavin, (2) tryptophan and tyrosine, or (3) riboflavin, tryptophan and tyrosine are deleted from medium prior to irradiation with any of the above fluorescent lamps. Toxic photoproducts are also formed when buffered salt solutions containing (a) riboflavin and tryptophan, (b) riboflavin and tyrosine, or (c) riboflavin, tryptophan and tyrosine are exposed to any of these light sources.

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