Fractional excretion of magnesium of chronic renal failure patients in Lagos, Nigeria.

Olajumoke Oladipo, J. Onubi, O. Awobusuyi, O. A. Afonja

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Abstract

The objective of this study was to explore the usefulness of the fractional excretion of magnesium (FEMg2+) in Nigerian chronic renal failure patients (mild to moderate) in determining the severity of renal insufficiency. Plasma and twenty-four hour urine samples were analysed for magnesium and creatinine in thirty-five chronic renal failure patients and twenty-five healthy controls. The mean fractional excretion of magnesium (FEMg2+) was 15.3%(13.6) in the patients and 6.1%(2.3) in the controls and this correlated negatively with the creatinine clearance in both groups (r = -0.343, p < 0.05) in patients and (r = -0.665, p < 0.001) in controls. There was a positive correlation between plasma creatinine and fractional excretion of magnesium in the patients (r = 0.463, p < 0.05) and controls (0.455, p < 0.05). FEMg2+ may therefore be a more sensitive indicator of renal insufficiency and may also be a better indicator of the progression of renal failure.

Original languageEnglish (US)
Pages (from-to)131-134
Number of pages4
JournalThe Nigerian postgraduate medical journal
Volume10
Issue number3
Publication statusPublished - Jan 1 2003

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

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