From nutritional immunology to drug development

Meghna Verma; Raquel Hontecillas; Vida Abedi; Andrew Leber; Pinyi Lu; Nuria Tubau-Juni; Josep Bassaganya-Riera

doi:10.1007/978-3-319-73238-1_4

From nutritional immunology to drug development

Meghna Verma, Raquel Hontecillas, Vida Abedi, Andrew Leber, Pinyi Lu, Nuria Tubau-Juni, Josep Bassaganya-Riera

Department of Public Health Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The chapter focuses on the key aspects of nutritional immunology that help accelerate the path to safer and more effective treatments. We review the complex network of interactions between diet, immune system, gut microbiome, and metabolism. We exemplify how advanced computational technologies such as artificial intelligence (AI) and machine learning methods combined with preclinical and translational models aid the discovery of novel immunoregulatory pathways. Further, we highlight nutritional immunology concepts translated to the development of novel therapeutics in immune mediated diseases such as IBD. Finally, we show how advancements in the field of nutritional immunology can be used to enable the development of predictive, preventive, and personalized path to safer and more effective drugs.

Original language	English (US)
Title of host publication	Accelerated Path to Cures
Publisher	Springer International Publishing
Pages	41-56
Number of pages	16
ISBN (Electronic)	9783319732381
ISBN (Print)	9783319732374
DOIs	https://doi.org/10.1007/978-3-319-73238-1_4
State	Published - Apr 25 2018

All Science Journal Classification (ASJC) codes

Medicine(all)
Immunology and Microbiology(all)
Computer Science(all)
Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-3-319-73238-1_4

Cite this

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AU - Bassaganya-Riera, Josep

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From nutritional immunology to drug development

Abstract

All Science Journal Classification (ASJC) codes

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