From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi.

David Peter Hughes, J. P.M. Araújo, R. G. Loreto, L. Quevillon, C. de Bekker, H. C. Evans

Research output: Chapter in Book/Report/Conference proceedingConference contribution

29 Citations (Scopus)

Abstract

Parasites can manipulate the behavior of their hosts in ways that increase either their direct fitness or transmission to new hosts. The Kingdom Fungi have evolved a diverse array of strategies to manipulate arthropod behavior resulting in some of the most complex and impressive examples of behavioral manipulation by parasites. Here we provide an overview of these different interactions and discuss them from an evolutionary perspective. We discuss parasite manipulation within the context of Niko Tinbergen's four questions (function, phylogeny, causation, and ontogeny) before detailing the proximate mechanisms by which fungi control arthropod behavior and the evolutionary pathways to such adaptations. We focus on some systems for which we have recently acquired new knowledge (such as the zombie ant fungus, Ophiocordyceps unilateralis s.l.), but a major goal is also to highlight how many interesting examples remain to be discovered and investigated. With this in mind, we also discuss likely examples of manipulated spiders that are largely unexplored ("zombie spiders"). Armed with advanced tools in evolutionary biology (from serial block face SEM to RNAseq) we can discover how the fungi, a group of microbes capable of coordinated activity, have evolved the ability to direct animal behavior. In short, we have the ability to understand how the organism without the brain controls the one with the brain. We hope such a goal, coupled with the knowledge that many diverse examples of control exist, will inspire other organismal biologists to study the complex adaptations that have arisen from "so simple a beginning.".

Original languageEnglish (US)
Title of host publicationGenetics and Molecular Biology of Entomopathogenic Fungi, 2016
EditorsRaymond J. St. Leger, Brian Lovett
PublisherAcademic Press Inc.
Pages437-469
Number of pages33
ISBN (Print)9780128046944
DOIs
StatePublished - Jan 1 2016

Publication series

NameAdvances in Genetics
Volume94
ISSN (Print)0065-2660

Fingerprint

Behavior Control
Fungi
Parasites
Spiders
Aptitude
Arthropods
Animal Behavior
Ants
Brain
Phylogeny
Causality

All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Hughes, D. P., Araújo, J. P. M., Loreto, R. G., Quevillon, L., de Bekker, C., & Evans, H. C. (2016). From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi. In R. J. St. Leger, & B. Lovett (Eds.), Genetics and Molecular Biology of Entomopathogenic Fungi, 2016 (pp. 437-469). (Advances in Genetics; Vol. 94). Academic Press Inc.. https://doi.org/10.1016/bs.adgen.2016.01.004
Hughes, David Peter ; Araújo, J. P.M. ; Loreto, R. G. ; Quevillon, L. ; de Bekker, C. ; Evans, H. C. / From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi. Genetics and Molecular Biology of Entomopathogenic Fungi, 2016. editor / Raymond J. St. Leger ; Brian Lovett. Academic Press Inc., 2016. pp. 437-469 (Advances in Genetics).
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Hughes, DP, Araújo, JPM, Loreto, RG, Quevillon, L, de Bekker, C & Evans, HC 2016, From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi. in RJ St. Leger & B Lovett (eds), Genetics and Molecular Biology of Entomopathogenic Fungi, 2016. Advances in Genetics, vol. 94, Academic Press Inc., pp. 437-469. https://doi.org/10.1016/bs.adgen.2016.01.004

From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi. / Hughes, David Peter; Araújo, J. P.M.; Loreto, R. G.; Quevillon, L.; de Bekker, C.; Evans, H. C.

Genetics and Molecular Biology of Entomopathogenic Fungi, 2016. ed. / Raymond J. St. Leger; Brian Lovett. Academic Press Inc., 2016. p. 437-469 (Advances in Genetics; Vol. 94).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Hughes DP, Araújo JPM, Loreto RG, Quevillon L, de Bekker C, Evans HC. From So Simple a Beginning. The Evolution of Behavioral Manipulation by Fungi. In St. Leger RJ, Lovett B, editors, Genetics and Molecular Biology of Entomopathogenic Fungi, 2016. Academic Press Inc. 2016. p. 437-469. (Advances in Genetics). https://doi.org/10.1016/bs.adgen.2016.01.004