Functional divergence of the duplicated AtKIN14a and AtKIN14b genes

Critical roles in Arabidopsis meiosis and gametophyte development

Li Quan, Rong Xiao, Wuxing Li, Sung Aeong Oh, Hongzhi Kong, J. Christian Ambrose, Jennelle L. Malcos, Richard Cyr, David Twell, Hong Ma

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Gene duplication is important for gene family evolution, allowing for functional divergence and innovation. In flowering plants, duplicated genes are widely observed, and functional redundancy of closely related duplicates has been reported, but few cases of functional divergence of close duplicates have been described. Here, we show that the Arabidopsis AtKIN14a and AtKIN14b genes encoding highly similar kinesins are two of the most closely related Arabidopsis paralogs, which were formed by a duplication event that occurred after the split of Arabidopsis and poplar. In addition, AtKIN14a and AtKIN14b exhibit varying degrees of coding sequence divergence. Further genetic studies of plants carrying atkin14a and/or atkin14b mutations indicate that, although these two genes have similar functions, there is clear evidence for functional divergence. Although both genes are important for male and female meiosis, AtKIN14a plays a more critical role in male meiosis than AtKIN14b. Moreover, either one of these two genes is necessary and sufficient for gametophyte development, indicating that they are redundant for this function. Therefore, AtKIN14a and AtKIN14b together play important roles in controlling plant reproductive development. Our results suggest that the AtKIN14a and AtKIN14b genes have retained similar functions in gametophyte development and female meiosis, but have evolved partially distinct functions in male meiosis, with AtKIN14a playing a more substantive role.

Original languageEnglish (US)
Pages (from-to)1013-1026
Number of pages14
JournalPlant Journal
Volume53
Issue number6
DOIs
StatePublished - Mar 1 2008

Fingerprint

Meiosis
Arabidopsis
meiosis
Genes
genes
Kinesin
Plant Genes
Gene Duplication
Plant Development
kinesin
gene duplication
Angiospermae
Mutation
mutation

All Science Journal Classification (ASJC) codes

  • Genetics
  • Plant Science
  • Cell Biology

Cite this

Quan, Li ; Xiao, Rong ; Li, Wuxing ; Oh, Sung Aeong ; Kong, Hongzhi ; Ambrose, J. Christian ; Malcos, Jennelle L. ; Cyr, Richard ; Twell, David ; Ma, Hong. / Functional divergence of the duplicated AtKIN14a and AtKIN14b genes : Critical roles in Arabidopsis meiosis and gametophyte development. In: Plant Journal. 2008 ; Vol. 53, No. 6. pp. 1013-1026.
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abstract = "Gene duplication is important for gene family evolution, allowing for functional divergence and innovation. In flowering plants, duplicated genes are widely observed, and functional redundancy of closely related duplicates has been reported, but few cases of functional divergence of close duplicates have been described. Here, we show that the Arabidopsis AtKIN14a and AtKIN14b genes encoding highly similar kinesins are two of the most closely related Arabidopsis paralogs, which were formed by a duplication event that occurred after the split of Arabidopsis and poplar. In addition, AtKIN14a and AtKIN14b exhibit varying degrees of coding sequence divergence. Further genetic studies of plants carrying atkin14a and/or atkin14b mutations indicate that, although these two genes have similar functions, there is clear evidence for functional divergence. Although both genes are important for male and female meiosis, AtKIN14a plays a more critical role in male meiosis than AtKIN14b. Moreover, either one of these two genes is necessary and sufficient for gametophyte development, indicating that they are redundant for this function. Therefore, AtKIN14a and AtKIN14b together play important roles in controlling plant reproductive development. Our results suggest that the AtKIN14a and AtKIN14b genes have retained similar functions in gametophyte development and female meiosis, but have evolved partially distinct functions in male meiosis, with AtKIN14a playing a more substantive role.",
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Functional divergence of the duplicated AtKIN14a and AtKIN14b genes : Critical roles in Arabidopsis meiosis and gametophyte development. / Quan, Li; Xiao, Rong; Li, Wuxing; Oh, Sung Aeong; Kong, Hongzhi; Ambrose, J. Christian; Malcos, Jennelle L.; Cyr, Richard; Twell, David; Ma, Hong.

In: Plant Journal, Vol. 53, No. 6, 01.03.2008, p. 1013-1026.

Research output: Contribution to journalArticle

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T2 - Critical roles in Arabidopsis meiosis and gametophyte development

AU - Quan, Li

AU - Xiao, Rong

AU - Li, Wuxing

AU - Oh, Sung Aeong

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