Functional mapping: How to map genes for phenotypic plasticity of development

Lidan Sun, Libo Jiang, Meixia Ye, Xuli Zhu, Jing Wang, Kirk Gosik, Rongling Wu

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Functional mapping is a statistical tool derived to map genes or quantitative trait loci (QTLs) that control the dynamic process of complex traits. In this chapter, we describe an innovative modification of functional mapping to characterize the genetic basis of phenotypic plasticity for the developmental pattern of phenotypic traits. Phenotypic plasticity is a phenomenon by which multiple phenotypes are produced by a single genotype in response to changing environment. Although phenotypic plasticity has been extensively studied in the past decades, new insights into its formation mechanisms can be gained by integrating developmental principles because environmentally induced phenotypes require time to form and build. The new framework for functional mapping enables geneticists to illustrate the genetic architecture of how QTLs cope with environment to regulate the developmental pattern and timing of phenotypic formation. Because of their role in guiding the evolution of complex phenotypes through environmental adaptation, the discoveries of these QTLs facilitate the synthesis of evo-devo and eco-devo.

Original languageEnglish (US)
Title of host publicationEvolutionary Biology
Subtitle of host publicationBiodiversification from Genotype to Phenotype
PublisherSpringer International Publishing
Number of pages15
ISBN (Electronic)9783319199320
ISBN (Print)9783319199313
StatePublished - Jul 10 2015

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)


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