Functional near-infrared spectroscopy in addiction treatment: Preliminary evidence as a biomarker of treatment response

Scott Bunce, Jonathan Harris, Kurtulus Izzetoglu, Hasan Ayaz, Meltem Izzetoglu, Kambiz Pourrezaei, Banu Onaral

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

There is growing evidence that there are functional changes in the brains of individuals with substance use disorders. Numerous studies utilizing functional magnetic resonance imaging (fMRI) have shown that drug cues elicit increased regional blood flow in reward-related brain areas among addicted participants that is not found among normal controls. This finding has prompted leading investigators to suggest fMRI might be useful as a diagnostic or prognostic biomarker of addiction severity. However, fMRI is too costly for routine use in most treatment facilities. Functional near-infrared spectroscopy (fNIRs) offers an alternative neuroimaging modality that is safe, affordable, and patient-friendly. This manuscript reviews evidence that fNIRs can be used to differentiate prefrontal cortical responses of current alcohol dependent participants from alcohol dependent patients in treatment for 90-180 days. Differential responses to both alcohol and natural reward cues in both groups suggests fNIRs might serve as a clinic-friendly neuroimaging technology to inform clinical practice.

Original languageEnglish (US)
Title of host publicationFoundations of Augmented Cognition - 7th International Conference, AC 2013, Held as Part of HCI International 2013, Proceedings
Pages250-258
Number of pages9
Volume8027 LNAI
DOIs
StatePublished - 2013
Event7th International Conference on Foundations of Augmented Cognition, AC 2013, Held as Part of 15th International Conference on Human-Computer Interaction, HCI International 2013 - Las Vegas, NV, United States
Duration: Jul 21 2013Jul 26 2013

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8027 LNAI
ISSN (Print)03029743
ISSN (Electronic)16113349

Other

Other7th International Conference on Foundations of Augmented Cognition, AC 2013, Held as Part of 15th International Conference on Human-Computer Interaction, HCI International 2013
CountryUnited States
CityLas Vegas, NV
Period7/21/137/26/13

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Theoretical Computer Science

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