Functionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange

Ken S. Feldman, Inanllely Y. Gonzalez, Jocelyn E. Brown

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.

Original languageEnglish (US)
Article number45701
Pages (from-to)3564-3566
Number of pages3
JournalTetrahedron Letters
Volume56
Issue number23
DOIs
StatePublished - May 25 2015

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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