Abstract The carbofunctionalization of 2-bromo-N-benzyl indole via lithium-bromide exchange is presented. The reaction scope is demonstrated by providing a variety of substrate examples that deliver carbofunctionalized products in good-to-excellent yields. The competition between nucleophilic addition and proton transfer is discussed.
|Original language||English (US)|
|Number of pages||3|
|State||Published - May 25 2015|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry