FUNCTIONALLY-ACTIVE POLYPHOSPHAZENES AS REACTION PRECURSORS TO BIOLOGICALLY-ACTIVE MACROMOLECULES.

Harry R. Allcock, Paul E. Austin, Thomas X. Neenan

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations

Abstract

The classical route for the synthesis of poly(organophosphazenes) involves the use of poly(dichlorophosphazene) as a reactive intermediate for halogen substitution reactions by organic nucleophiles. Such reactions have been employed for the binding of a wide range of biologically active organic units, including catecholamines, polypeptides, procaine, sulfadiazine, etc. In at least one case (dopamine) biological activity has been demonstrated even by the solid, reagent-bound polymer.

Original languageEnglish (US)
Number of pages1
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume26
Issue number1
StatePublished - Apr 1985

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics

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