GABA as an inhibitory transmitter in the pigeon isthmo-tectal pathway

Dominik Felix, Gang Yi Wu, Shu Rong Wang

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

In the present investigation, the effects of inhibitory amino acids and their antagonists were tested on isthmo-tectal projection in the pigeon. The majority of superficial tectal cells are inhibited following stimulation of the parvocellular division of nucleus isthmi. A smaller portion of tectal cells showed excitatory responses followed by an inhibitory period. Both inhibitory mechanisms are blocked by the specific γ-aminobutyric acid (GABA)-antagonist bicuculline but not by strychnine. Our results support the idea that GABA acts as an inhibitory neurotransmitter in the pigeon isthmo-tectal pathways.

Original languageEnglish (US)
Pages (from-to)212-214
Number of pages3
JournalNeuroscience letters
Volume169
Issue number1-2
DOIs
StatePublished - Mar 14 1994

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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