Galaxy: A platform for interactive large-scale genome analysis

Belinda Giardine, Cathy Riemer, Ross C. Hardison, Richard Burhans, Laura Elnitski, Prachi Shah, Yi Zhang, Daniel Blankenberg, Istvan Albert, James Taylor, Webb Miller, W. James Kent, Anton Nekrutenko

Research output: Contribution to journalArticle

1364 Scopus citations

Abstract

Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu.

Original languageEnglish (US)
Pages (from-to)1451-1455
Number of pages5
JournalGenome research
Volume15
Issue number10
DOIs
StatePublished - Oct 1 2005

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

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    Giardine, B., Riemer, C., Hardison, R. C., Burhans, R., Elnitski, L., Shah, P., Zhang, Y., Blankenberg, D., Albert, I., Taylor, J., Miller, W., Kent, W. J., & Nekrutenko, A. (2005). Galaxy: A platform for interactive large-scale genome analysis. Genome research, 15(10), 1451-1455. https://doi.org/10.1101/gr.4086505