Galaxy: A web-based genome analysis tool for experimentalists

Daniel Blankenberg, Gregory Von Kuster, Nathaniel Coraor, Guruprasad Ananda, Ross Lazarus, Mary Mangan, Anton Nekrutenko, James Taylor

Research output: Contribution to journalReview articlepeer-review

981 Scopus citations

Abstract

High-throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus, making sense of high-throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is distributed both as a publicly available Web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual laboratories. Either way, it allows experimentalists without informatics or programming expertise to perform complex large-scale analysis with just a Web browser.

Original languageEnglish (US)
Pages (from-to)19.10.1-19.10.21
JournalCurrent Protocols in Molecular Biology
Issue numberSUPPL. 89
DOIs
StatePublished - 2010

All Science Journal Classification (ASJC) codes

  • Molecular Biology

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