TY - CHAP
T1 - Gambogic acid and its role in chronic diseases
AU - Pandey, Manoj K.
AU - Karelia, Deepkamal
AU - Amin, Shantu G.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Kokum, a spice derived from the fruit of the Garcinia hanburyi tree, is traditionally used in Ayurvedic medicines to facilitate digestion and to treat sores, dermatitis, diarrhoea, dysentery, and ear infection. One of the major active components of kokum is gambogic acid, also known as guttic acid, guttatic acid, beta-guttilactone, and beta-guttiferin. Gambogic acid’s anti-proliferative, anti-bacterial; antioxidant and anti-inflammatory effects result from its modulation of numerous cell-signaling intermediates. This chapter discusses the sources, chemical components, mechanism of action, and disease targets of the kokum spice.
AB - Kokum, a spice derived from the fruit of the Garcinia hanburyi tree, is traditionally used in Ayurvedic medicines to facilitate digestion and to treat sores, dermatitis, diarrhoea, dysentery, and ear infection. One of the major active components of kokum is gambogic acid, also known as guttic acid, guttatic acid, beta-guttilactone, and beta-guttiferin. Gambogic acid’s anti-proliferative, anti-bacterial; antioxidant and anti-inflammatory effects result from its modulation of numerous cell-signaling intermediates. This chapter discusses the sources, chemical components, mechanism of action, and disease targets of the kokum spice.
UR - http://www.scopus.com/inward/record.url?scp=84988923217&partnerID=8YFLogxK
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U2 - 10.1007/978-3-319-41334-1_15
DO - 10.1007/978-3-319-41334-1_15
M3 - Chapter
C2 - 27671824
AN - SCOPUS:84988923217
T3 - Advances in Experimental Medicine and Biology
SP - 375
EP - 395
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -
