Gas transport in the conducting airways

An axisymmetric single-path model

Srinath Madasu, Ali Borhan, James Ultman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An axisymmetric single-path model (ASPM) for gas transport in the lower airways is developed and validated. A single airway path is represented by a series of straight tube segments interconnected by leaky transition regions that provide for flow loss at the airway bifurcations. The finite element method is used to solve the Navier-Stokes, continuity, and species convective-diffusion equations for the flow field and the species concentration distribution in the airways. The model is validated by comparing its predictions to the following experimental measurements: 1) dispersion coefficients for unsteady dispersion of an inhaled pulse of inert gas (benzene) along an airway path encompassing five generations in a scaled-up model of Weibel's symmetric airway geometry, and 2) mass transfer coefficients for steady inspiratory-directed flow of a reactive gas (formaldehyde) in both a single bifurcation and an airway path incorporating three generations of a symmetrically-branched physical model of the airways. For the latter problem, ASPM predictions are also compared with the results of three-dimensional finite element computations in the branched airway geometry. The ASPM results for the dispersion and mass transfer coefficients compare quantitatively well with both the experimental measurements and three-dimensional simulations.

Original languageEnglish (US)
Title of host publication05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings
Pages8917
Number of pages1
StatePublished - 2005
Event05AIChE: 2005 AIChE Annual Meeting and Fall Showcase - Cincinnati, OH, United States
Duration: Oct 30 2005Nov 4 2005

Other

Other05AIChE: 2005 AIChE Annual Meeting and Fall Showcase
CountryUnited States
CityCincinnati, OH
Period10/30/0511/4/05

Fingerprint

Gases
Mass transfer
Bifurcation (mathematics)
Geometry
Inert gases
Formaldehyde
Benzene
Flow fields
Finite element method

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Madasu, S., Borhan, A., & Ultman, J. (2005). Gas transport in the conducting airways: An axisymmetric single-path model. In 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings (pp. 8917)
Madasu, Srinath ; Borhan, Ali ; Ultman, James. / Gas transport in the conducting airways : An axisymmetric single-path model. 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 2005. pp. 8917
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Madasu, S, Borhan, A & Ultman, J 2005, Gas transport in the conducting airways: An axisymmetric single-path model. in 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. pp. 8917, 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Cincinnati, OH, United States, 10/30/05.

Gas transport in the conducting airways : An axisymmetric single-path model. / Madasu, Srinath; Borhan, Ali; Ultman, James.

05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 2005. p. 8917.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Madasu S, Borhan A, Ultman J. Gas transport in the conducting airways: An axisymmetric single-path model. In 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, Conference Proceedings. 2005. p. 8917