Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children: Result from 25 districts of Northeastern China

Da Wang, Zhengmin Qian, Jing Wang, Mingan Yang, Yungling Leo Lee, Fan Liu, Miao Miao Liu, Yang Zhao, Yu Qin Liu, Mei Meng Huang, Yang Liu, Jing Sun, Yi Zhe Liu, Chen Chen Wu, Guang Hui Dong

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective: The relationship between obesity and allergic respiratory diseases in childhood is still controversial. Furthermore, significant debate on the issue of whether or not gender modifies this association also exists due to inconsistent findings. The objective of this study is to evaluate the association between obesity and respiratory health in children, and to investigate the modifications of gender on this association. Methods: 30056 children (aged 2-14 years) were randomly selected from 25 districts within 7 cities in Northeastern China in 2009. A standard questionnaire from the American Thoracic Society was used to characterize the childrens' histories of respiratory symptoms and illnesses. Child weight and height were measured, and obesity was calculated with an age and sex-specific body mass index. Results: The overall prevalence rates of obesity and overweightness were 14.08% and 12.32%, respectively. Compared to the children with normal body weights, asthma and asthma-related symptoms were more prevalent in overweight and obese children. Analysis stratified by gender showed that obesity was associated with more respiratory symptoms and diseases in females than in males. A significant association between obesity and diagnosed asthma [adjusted odds ratio (aOR)=1.28; 95% confidence interval (CI): 1.02-1.60], as well as current wheezing (aOR=1.46; 95%CI: 1.20-1.79) was found in females but not in males. Conclusions: There is an association between asthma symptoms and obesity in these Chinese children, and obesity had a significantly larger effect on females than males.

Original languageEnglish (US)
Pages (from-to)508-514
Number of pages7
JournalJournal of Asthma
Volume51
Issue number5
DOIs
StatePublished - Jan 1 2014

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China
Asthma
Obesity
Odds Ratio
Confidence Intervals
Ideal Body Weight
Pediatric Obesity
Respiratory Sounds
Body Mass Index
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Wang, Da ; Qian, Zhengmin ; Wang, Jing ; Yang, Mingan ; Lee, Yungling Leo ; Liu, Fan ; Liu, Miao Miao ; Zhao, Yang ; Liu, Yu Qin ; Huang, Mei Meng ; Liu, Yang ; Sun, Jing ; Liu, Yi Zhe ; Wu, Chen Chen ; Dong, Guang Hui. / Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children : Result from 25 districts of Northeastern China. In: Journal of Asthma. 2014 ; Vol. 51, No. 5. pp. 508-514.
@article{39fb60c708cc4a6aaad7a760dcd1d90f,
title = "Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children: Result from 25 districts of Northeastern China",
abstract = "Objective: The relationship between obesity and allergic respiratory diseases in childhood is still controversial. Furthermore, significant debate on the issue of whether or not gender modifies this association also exists due to inconsistent findings. The objective of this study is to evaluate the association between obesity and respiratory health in children, and to investigate the modifications of gender on this association. Methods: 30056 children (aged 2-14 years) were randomly selected from 25 districts within 7 cities in Northeastern China in 2009. A standard questionnaire from the American Thoracic Society was used to characterize the childrens' histories of respiratory symptoms and illnesses. Child weight and height were measured, and obesity was calculated with an age and sex-specific body mass index. Results: The overall prevalence rates of obesity and overweightness were 14.08{\%} and 12.32{\%}, respectively. Compared to the children with normal body weights, asthma and asthma-related symptoms were more prevalent in overweight and obese children. Analysis stratified by gender showed that obesity was associated with more respiratory symptoms and diseases in females than in males. A significant association between obesity and diagnosed asthma [adjusted odds ratio (aOR)=1.28; 95{\%} confidence interval (CI): 1.02-1.60], as well as current wheezing (aOR=1.46; 95{\%}CI: 1.20-1.79) was found in females but not in males. Conclusions: There is an association between asthma symptoms and obesity in these Chinese children, and obesity had a significantly larger effect on females than males.",
author = "Da Wang and Zhengmin Qian and Jing Wang and Mingan Yang and Lee, {Yungling Leo} and Fan Liu and Liu, {Miao Miao} and Yang Zhao and Liu, {Yu Qin} and Huang, {Mei Meng} and Yang Liu and Jing Sun and Liu, {Yi Zhe} and Wu, {Chen Chen} and Dong, {Guang Hui}",
year = "2014",
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doi = "10.3109/02770903.2014.892963",
language = "English (US)",
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pages = "508--514",
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Wang, D, Qian, Z, Wang, J, Yang, M, Lee, YL, Liu, F, Liu, MM, Zhao, Y, Liu, YQ, Huang, MM, Liu, Y, Sun, J, Liu, YZ, Wu, CC & Dong, GH 2014, 'Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children: Result from 25 districts of Northeastern China', Journal of Asthma, vol. 51, no. 5, pp. 508-514. https://doi.org/10.3109/02770903.2014.892963

Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children : Result from 25 districts of Northeastern China. / Wang, Da; Qian, Zhengmin; Wang, Jing; Yang, Mingan; Lee, Yungling Leo; Liu, Fan; Liu, Miao Miao; Zhao, Yang; Liu, Yu Qin; Huang, Mei Meng; Liu, Yang; Sun, Jing; Liu, Yi Zhe; Wu, Chen Chen; Dong, Guang Hui.

In: Journal of Asthma, Vol. 51, No. 5, 01.01.2014, p. 508-514.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30056 children

T2 - Result from 25 districts of Northeastern China

AU - Wang, Da

AU - Qian, Zhengmin

AU - Wang, Jing

AU - Yang, Mingan

AU - Lee, Yungling Leo

AU - Liu, Fan

AU - Liu, Miao Miao

AU - Zhao, Yang

AU - Liu, Yu Qin

AU - Huang, Mei Meng

AU - Liu, Yang

AU - Sun, Jing

AU - Liu, Yi Zhe

AU - Wu, Chen Chen

AU - Dong, Guang Hui

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objective: The relationship between obesity and allergic respiratory diseases in childhood is still controversial. Furthermore, significant debate on the issue of whether or not gender modifies this association also exists due to inconsistent findings. The objective of this study is to evaluate the association between obesity and respiratory health in children, and to investigate the modifications of gender on this association. Methods: 30056 children (aged 2-14 years) were randomly selected from 25 districts within 7 cities in Northeastern China in 2009. A standard questionnaire from the American Thoracic Society was used to characterize the childrens' histories of respiratory symptoms and illnesses. Child weight and height were measured, and obesity was calculated with an age and sex-specific body mass index. Results: The overall prevalence rates of obesity and overweightness were 14.08% and 12.32%, respectively. Compared to the children with normal body weights, asthma and asthma-related symptoms were more prevalent in overweight and obese children. Analysis stratified by gender showed that obesity was associated with more respiratory symptoms and diseases in females than in males. A significant association between obesity and diagnosed asthma [adjusted odds ratio (aOR)=1.28; 95% confidence interval (CI): 1.02-1.60], as well as current wheezing (aOR=1.46; 95%CI: 1.20-1.79) was found in females but not in males. Conclusions: There is an association between asthma symptoms and obesity in these Chinese children, and obesity had a significantly larger effect on females than males.

AB - Objective: The relationship between obesity and allergic respiratory diseases in childhood is still controversial. Furthermore, significant debate on the issue of whether or not gender modifies this association also exists due to inconsistent findings. The objective of this study is to evaluate the association between obesity and respiratory health in children, and to investigate the modifications of gender on this association. Methods: 30056 children (aged 2-14 years) were randomly selected from 25 districts within 7 cities in Northeastern China in 2009. A standard questionnaire from the American Thoracic Society was used to characterize the childrens' histories of respiratory symptoms and illnesses. Child weight and height were measured, and obesity was calculated with an age and sex-specific body mass index. Results: The overall prevalence rates of obesity and overweightness were 14.08% and 12.32%, respectively. Compared to the children with normal body weights, asthma and asthma-related symptoms were more prevalent in overweight and obese children. Analysis stratified by gender showed that obesity was associated with more respiratory symptoms and diseases in females than in males. A significant association between obesity and diagnosed asthma [adjusted odds ratio (aOR)=1.28; 95% confidence interval (CI): 1.02-1.60], as well as current wheezing (aOR=1.46; 95%CI: 1.20-1.79) was found in females but not in males. Conclusions: There is an association between asthma symptoms and obesity in these Chinese children, and obesity had a significantly larger effect on females than males.

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