Generation and intramolecular cationic cyclizations of N-tosylimines derived from enolizable aldehydes

Michael J. Melnick, Alan J. Freyer, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

Boron trifluoride etherate promotes both in situ formation of N-tosyliminium complexes from olefinic enolizable aldehydes and N-sulfinyl-p-toluenesulfonamide, and subsequent intramolecular electrophilic cyclization to afford homoallylic amines.

Original languageEnglish (US)
Pages (from-to)3891-3894
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number32
DOIs
StatePublished - 1988

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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