Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl) aziridines: Application in the construction of the communesin ring system

Seth L. Crawley, Raymond L. Funk

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.

Original languageEnglish (US)
Pages (from-to)3995-3998
Number of pages4
JournalOrganic Letters
Volume8
Issue number18
DOIs
StatePublished - Aug 31 2006

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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