Genes acquired by horizontal transfer are potentially involved in the evolution of phytopathogenicity in moniliophthora perniciosa and moniliophthora roreri, two of the major pathogens of cacao

Ricardo Augusto Tiburcio, Gustavo Gilson Lacerda Costa, Marcelo Falsarella Carazzolle, Jorge Mauŕcio Costa Mondego, Stephen C. Schuster, John Edward Carlson, Mark Guiltinan, Bryan A. Bailey, Piotr Mieczkowski, Lyndel W. Meinhardt, Gonçalo Amarante Guimarães Pereira

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Moniliophthora perniciosa and Moniliophthora roreri are phytopathogenic basidiomycete species that infect cacao causing two important diseases in this crop: Witches Broom and Frosty Pod Rot, respectively. The ability of species from this genus (Moniliophthora) to cause disease is exceptional in the family Marasmiaceae. Species in closely related genera including, Marasmius, Crinipellis, and Chaetocalathus, are mainly saprotrophs and are not known to cause disease. In this study, the possibility that this phytopathogenic lifestyle has been acquired by horizontal gene transfer (HGT) was investigated. A stringent genome comparison pipeline was used to identify potential genes that have been obtained by Moniliophthora through HGT. This search led to the identification of three genes: a metallo-dependent hydrolase (MDH), a mannitol phosphate dehydrogenase (MPDH), and a family of necrosis-inducing proteins (NEPs). Phylogenetic analysis of these genes suggests that Moniliophthora acquired NEPs from oomycetes, MDH from actinobacteria and MPDH from firmicutes. Based on the known gene functions and on previous studies of M. perniciosa infection and development, a correlation between gene acquisition and the evolution of the phytopathogenic genus Moniliophthora can be postulated.

Original languageEnglish (US)
Pages (from-to)85-97
Number of pages13
JournalJournal of Molecular Evolution
Volume70
Issue number1
DOIs
StatePublished - Jan 1 2010

Fingerprint

Moniliophthora roreri
Moniliophthora perniciosa
Moniliophthora
Horizontal Gene Transfer
Cacao
pathogen
Mannitol Dehydrogenases
Mannitol Phosphates
gene
pathogens
Genes
gene transfer
Hydrolases
hydrolases
mannitol
genes
Marasmius
Crinipellis
Marasmiaceae
necrosis

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

Tiburcio, Ricardo Augusto ; Costa, Gustavo Gilson Lacerda ; Carazzolle, Marcelo Falsarella ; Mondego, Jorge Mauŕcio Costa ; Schuster, Stephen C. ; Carlson, John Edward ; Guiltinan, Mark ; Bailey, Bryan A. ; Mieczkowski, Piotr ; Meinhardt, Lyndel W. ; Pereira, Gonçalo Amarante Guimarães. / Genes acquired by horizontal transfer are potentially involved in the evolution of phytopathogenicity in moniliophthora perniciosa and moniliophthora roreri, two of the major pathogens of cacao. In: Journal of Molecular Evolution. 2010 ; Vol. 70, No. 1. pp. 85-97.
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abstract = "Moniliophthora perniciosa and Moniliophthora roreri are phytopathogenic basidiomycete species that infect cacao causing two important diseases in this crop: Witches Broom and Frosty Pod Rot, respectively. The ability of species from this genus (Moniliophthora) to cause disease is exceptional in the family Marasmiaceae. Species in closely related genera including, Marasmius, Crinipellis, and Chaetocalathus, are mainly saprotrophs and are not known to cause disease. In this study, the possibility that this phytopathogenic lifestyle has been acquired by horizontal gene transfer (HGT) was investigated. A stringent genome comparison pipeline was used to identify potential genes that have been obtained by Moniliophthora through HGT. This search led to the identification of three genes: a metallo-dependent hydrolase (MDH), a mannitol phosphate dehydrogenase (MPDH), and a family of necrosis-inducing proteins (NEPs). Phylogenetic analysis of these genes suggests that Moniliophthora acquired NEPs from oomycetes, MDH from actinobacteria and MPDH from firmicutes. Based on the known gene functions and on previous studies of M. perniciosa infection and development, a correlation between gene acquisition and the evolution of the phytopathogenic genus Moniliophthora can be postulated.",
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Genes acquired by horizontal transfer are potentially involved in the evolution of phytopathogenicity in moniliophthora perniciosa and moniliophthora roreri, two of the major pathogens of cacao. / Tiburcio, Ricardo Augusto; Costa, Gustavo Gilson Lacerda; Carazzolle, Marcelo Falsarella; Mondego, Jorge Mauŕcio Costa; Schuster, Stephen C.; Carlson, John Edward; Guiltinan, Mark; Bailey, Bryan A.; Mieczkowski, Piotr; Meinhardt, Lyndel W.; Pereira, Gonçalo Amarante Guimarães.

In: Journal of Molecular Evolution, Vol. 70, No. 1, 01.01.2010, p. 85-97.

Research output: Contribution to journalArticle

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T1 - Genes acquired by horizontal transfer are potentially involved in the evolution of phytopathogenicity in moniliophthora perniciosa and moniliophthora roreri, two of the major pathogens of cacao

AU - Tiburcio, Ricardo Augusto

AU - Costa, Gustavo Gilson Lacerda

AU - Carazzolle, Marcelo Falsarella

AU - Mondego, Jorge Mauŕcio Costa

AU - Schuster, Stephen C.

AU - Carlson, John Edward

AU - Guiltinan, Mark

AU - Bailey, Bryan A.

AU - Mieczkowski, Piotr

AU - Meinhardt, Lyndel W.

AU - Pereira, Gonçalo Amarante Guimarães

PY - 2010/1/1

Y1 - 2010/1/1

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