Genes in context: Probing the genetics of fracture resistance

Neil Sharkey, Dean H. Lang

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.

Original languageEnglish (US)
Pages (from-to)86-96
Number of pages11
JournalExercise and Sport Sciences Reviews
Volume35
Issue number3
DOIs
StatePublished - Jul 1 2007

Fingerprint

Genetic Phenomena
Quantitative Trait Loci
Bone and Bones
Genes

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

@article{817da48104d24c3894440b1770bbb8d1,
title = "Genes in context: Probing the genetics of fracture resistance",
abstract = "Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.",
author = "Neil Sharkey and Lang, {Dean H.}",
year = "2007",
month = "7",
day = "1",
doi = "10.1097/jes.0b013e31809ff2ca",
language = "English (US)",
volume = "35",
pages = "86--96",
journal = "Exercise and Sport Sciences Reviews",
issn = "0091-6331",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

Genes in context : Probing the genetics of fracture resistance. / Sharkey, Neil; Lang, Dean H.

In: Exercise and Sport Sciences Reviews, Vol. 35, No. 3, 01.07.2007, p. 86-96.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Genes in context

T2 - Probing the genetics of fracture resistance

AU - Sharkey, Neil

AU - Lang, Dean H.

PY - 2007/7/1

Y1 - 2007/7/1

N2 - Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.

AB - Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.

UR - http://www.scopus.com/inward/record.url?scp=34447326675&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447326675&partnerID=8YFLogxK

U2 - 10.1097/jes.0b013e31809ff2ca

DO - 10.1097/jes.0b013e31809ff2ca

M3 - Review article

C2 - 17620926

AN - SCOPUS:34447326675

VL - 35

SP - 86

EP - 96

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

SN - 0091-6331

IS - 3

ER -