Genome sequence of the anterograde-spread-defective herpes simplex virus 1 strain MacIntyre

Moriah L. Szpara, Yolanda R. Tafuri, Lance Parsons, Jacob T. Shreve, Esteban A. Engel, L. W. Enquist

Research output: Contribution to journalArticle

4 Scopus citations


We used paired-end Illumina deep sequencing and de novo assembly to determine the genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a unique limitation in its neuronal spread, moving solely in the retrograde direction.

Original languageEnglish (US)
Article numbere01161-14
JournalGenome Announcements
Issue number6
StatePublished - Jan 1 2014


All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

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