Genomic characterization of a novel avian arthritis orthoreovirus variant by next-generation sequencing

Yi Tang, Huaguang Lu

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

By using next-generation sequencing (NGS) technology, we have identified a divergent avian orthoreovirus (ARV) field variant (Reo/PA/Broiler/15511/13, or PA15511), isolated from broiler chickens with viral arthritis in Pennsylvania in 2013. The complete genome of the PA15511 field strain was 23,495 bp in length with 10 dsRNA segments encoding 12 viral proteins. The lengths of the genomic segments ranged from 1192 bp (S4) to 3958 bp (L1). Genomic analysis has revealed that this virus is distinct from reference ARV strains and meets criteria for a new or novel strain.

Original languageEnglish (US)
Pages (from-to)2629-2632
Number of pages4
JournalArchives of Virology
Volume160
Issue number10
DOIs
StatePublished - Oct 30 2015

All Science Journal Classification (ASJC) codes

  • Virology

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