Genomic variability among enteric pathogens: The case of the mutS-rpoS intergenic region

Michael L. Kotewicz, Eric W. Brown, J. Eugene LeClerc, Thomas A. Cebula

Research output: Contribution to journalShort survey

26 Scopus citations

Abstract

The mutS-rpoS intergenic region of enteric bacteria ranges in size from 88 bp in Yersinia to >12 000 bp in Salmonella. We interpret this expansion as the result of the horizontal transfer of segments of DNA from diverse origins. Both comparative genomic analysis and selective sequencing of a variety of Escherichia coli pathogens have provided additional evidence for reassortment of segments within this region.

Original languageEnglish (US)
Pages (from-to)2-6
Number of pages5
JournalTrends in Microbiology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2003

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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