Genomic variability among enteric pathogens

The case of the mutS-rpoS intergenic region

Michael L. Kotewicz, Eric Wayne Brown, J. Eugene LeClerc, Thomas A. Cebula

Research output: Contribution to journalShort survey

26 Citations (Scopus)

Abstract

The mutS-rpoS intergenic region of enteric bacteria ranges in size from 88 bp in Yersinia to >12 000 bp in Salmonella. We interpret this expansion as the result of the horizontal transfer of segments of DNA from diverse origins. Both comparative genomic analysis and selective sequencing of a variety of Escherichia coli pathogens have provided additional evidence for reassortment of segments within this region.

Original languageEnglish (US)
Pages (from-to)2-6
Number of pages5
JournalTrends in Microbiology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2003

Fingerprint

Yersinia
Intergenic DNA
Enterobacteriaceae
Salmonella
Escherichia coli
DNA

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

Cite this

Kotewicz, Michael L. ; Brown, Eric Wayne ; LeClerc, J. Eugene ; Cebula, Thomas A. / Genomic variability among enteric pathogens : The case of the mutS-rpoS intergenic region. In: Trends in Microbiology. 2003 ; Vol. 11, No. 1. pp. 2-6.
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Genomic variability among enteric pathogens : The case of the mutS-rpoS intergenic region. / Kotewicz, Michael L.; Brown, Eric Wayne; LeClerc, J. Eugene; Cebula, Thomas A.

In: Trends in Microbiology, Vol. 11, No. 1, 01.01.2003, p. 2-6.

Research output: Contribution to journalShort survey

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