Gigantic cutaneous horns of the scalp: Lesions with a gross similarity to the horns of animals: A report of four cases

Michal Michal, Michele Bisceglia, Antonio Di Mattia, Luis Requena, Julie C. Fanburg-Smith, Petr Mukensnabl, Ondrej Hes, Frantisek Cada

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Gigantic cutaneous horns, grossly similar to the horns seen in animals, are exceedingly rare in humans. After finding one case in practice, we searched our departmental files for similar cases and examined them grossly and microscopically. Four cases were identified. All occurred as solitary lesions in older women on the parietal-occipital region of the scalp. They had a growth history of up to 30 years; the women hid these horns in their hair. Grossly, the horns were yellow-grey, and there were shallow furrows running along the length of the horns. The length ranged from 17 to 25 cm, and the width was up to 2.5 cm. All four lesions showed similar histologic changes. Microscopically, the gigantic horns consisted of a mixture of squamous epithelial cells and tricholemmal keratinized debris. In one case the base of the horn was directly connected with a mass composed of benign tricholemmal cysts of the scalp. Mitoses were common, but atypical mitoses were not observed. The nuclei of the squamous cells were bland without pleomorphism, hyperchromasia, or atypia. Follow-up of all patients was uneventful: all patients were well and without signs of recurrence or metastasis 2-15 years after the surgical excision. Gigantic cutaneous horns are rare and benign. We think that they represent an extremely well-differentiated variant of proliferating tricholemmal tumor with an unusual and remarkable gross pattern.

Original languageEnglish (US)
Pages (from-to)789-794
Number of pages6
JournalAmerican Journal of Surgical Pathology
Volume26
Issue number6
DOIs
StatePublished - Jun 3 2002

Fingerprint

Horns
Scalp
Skin
Mitosis
Epithelial Cells
Occipital Lobe
Parietal Lobe
Running
Hair
Neoplasm Metastasis
Recurrence
Growth
Neoplasms

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

Cite this

Michal, Michal ; Bisceglia, Michele ; Di Mattia, Antonio ; Requena, Luis ; Fanburg-Smith, Julie C. ; Mukensnabl, Petr ; Hes, Ondrej ; Cada, Frantisek. / Gigantic cutaneous horns of the scalp : Lesions with a gross similarity to the horns of animals: A report of four cases. In: American Journal of Surgical Pathology. 2002 ; Vol. 26, No. 6. pp. 789-794.
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abstract = "Gigantic cutaneous horns, grossly similar to the horns seen in animals, are exceedingly rare in humans. After finding one case in practice, we searched our departmental files for similar cases and examined them grossly and microscopically. Four cases were identified. All occurred as solitary lesions in older women on the parietal-occipital region of the scalp. They had a growth history of up to 30 years; the women hid these horns in their hair. Grossly, the horns were yellow-grey, and there were shallow furrows running along the length of the horns. The length ranged from 17 to 25 cm, and the width was up to 2.5 cm. All four lesions showed similar histologic changes. Microscopically, the gigantic horns consisted of a mixture of squamous epithelial cells and tricholemmal keratinized debris. In one case the base of the horn was directly connected with a mass composed of benign tricholemmal cysts of the scalp. Mitoses were common, but atypical mitoses were not observed. The nuclei of the squamous cells were bland without pleomorphism, hyperchromasia, or atypia. Follow-up of all patients was uneventful: all patients were well and without signs of recurrence or metastasis 2-15 years after the surgical excision. Gigantic cutaneous horns are rare and benign. We think that they represent an extremely well-differentiated variant of proliferating tricholemmal tumor with an unusual and remarkable gross pattern.",
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Gigantic cutaneous horns of the scalp : Lesions with a gross similarity to the horns of animals: A report of four cases. / Michal, Michal; Bisceglia, Michele; Di Mattia, Antonio; Requena, Luis; Fanburg-Smith, Julie C.; Mukensnabl, Petr; Hes, Ondrej; Cada, Frantisek.

In: American Journal of Surgical Pathology, Vol. 26, No. 6, 03.06.2002, p. 789-794.

Research output: Contribution to journalArticle

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T2 - Lesions with a gross similarity to the horns of animals: A report of four cases

AU - Michal, Michal

AU - Bisceglia, Michele

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