Glucose transporter Glut 5 expression in microglial cells

Jennifer Payne, Fran Maher, Ian Simpson, Linda Mattice, Peter Davies

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Glut 5 is a member of a family of facilitative glucose transporter proteins that are involved in the transportation of glucose and/or fructose across plasma membranes. Glut 5 is one of three isoforms expressed in brain. Using immunocytochemical and immunoblotting techniques in formalin fixed tissue, we have shown that Glut 5 is exclusively expressed in microglial cells of the human and rat brain. Our data demonstrate that unlike other microglial markers, Glut 5 can be used as a microglial marker in formalin fixed tissue.

Original languageEnglish (US)
Pages (from-to)327-331
Number of pages5
JournalGlia
Volume21
Issue number3
DOIs
StatePublished - Nov 1 1997

Fingerprint

Facilitative Glucose Transport Proteins
Formaldehyde
Brain
Fructose
Immunoblotting
Protein Isoforms
Cell Membrane
Glucose
Proteins

All Science Journal Classification (ASJC) codes

  • Neurology
  • Cellular and Molecular Neuroscience

Cite this

Payne, Jennifer ; Maher, Fran ; Simpson, Ian ; Mattice, Linda ; Davies, Peter. / Glucose transporter Glut 5 expression in microglial cells. In: Glia. 1997 ; Vol. 21, No. 3. pp. 327-331.
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Glucose transporter Glut 5 expression in microglial cells. / Payne, Jennifer; Maher, Fran; Simpson, Ian; Mattice, Linda; Davies, Peter.

In: Glia, Vol. 21, No. 3, 01.11.1997, p. 327-331.

Research output: Contribution to journalArticle

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