Growth Factors and Wound Healing in the Hamster

KIM LEITZEL, CHERYL CANO, James Marks, Allan Lipton

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We have investigated the effect of topically applied mitogenic preparations on the healing of full‐thickness skin wounds in the Syrian hamster. In an attempt to accelerate the healing process, dexamethasone and insulin, platelet‐derived growth factor, fibroblast growth factor, thrombin, defined medium F for fibroblasts, liver cell supernatant, epidermal growth factor, and colostrum were applied to the wounds. These mitogens had no significant influence on the rate of wound contraction or on the time to complete healing in full‐thickness, noncompromised skin wounds in this animal model. 1985 American Society for Dermatologic Surgery, Inc.

Original languageEnglish (US)
Pages (from-to)617-627
Number of pages11
JournalThe Journal of Dermatologic Surgery and Oncology
Volume11
Issue number6
DOIs
StatePublished - Jan 1 1985

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Cricetinae
Wound Healing
Intercellular Signaling Peptides and Proteins
Wounds and Injuries
Dermatologic Surgical Procedures
Skin
Colostrum
Fibroblast Growth Factors
Mesocricetus
Mitogens
Epidermal Growth Factor
Thrombin
Dexamethasone
Animal Models
Fibroblasts
Insulin
Liver

All Science Journal Classification (ASJC) codes

  • Oncology
  • Dermatology

Cite this

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Growth Factors and Wound Healing in the Hamster. / LEITZEL, KIM; CANO, CHERYL; Marks, James; Lipton, Allan.

In: The Journal of Dermatologic Surgery and Oncology, Vol. 11, No. 6, 01.01.1985, p. 617-627.

Research output: Contribution to journalArticle

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