GTPase signaling

Bridging the GAP between ARF and Rho

Lorraine C. Santy, James E. Casanova

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

Original languageEnglish (US)
Pages (from-to)R360-R362
JournalCurrent Biology
Volume12
Issue number10
DOIs
StatePublished - May 14 2002

Fingerprint

GTPase-activating proteins
GTPase-Activating Proteins
rho GTP-Binding Proteins
GTP Phosphohydrolases
guanosinetriphosphatase
Actins
Proteins
Membranes
Actin Cytoskeleton
microfilaments
traffic
rho GTPase-activating protein
Protein Domains

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Santy, Lorraine C. ; Casanova, James E. / GTPase signaling : Bridging the GAP between ARF and Rho. In: Current Biology. 2002 ; Vol. 12, No. 10. pp. R360-R362.
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GTPase signaling : Bridging the GAP between ARF and Rho. / Santy, Lorraine C.; Casanova, James E.

In: Current Biology, Vol. 12, No. 10, 14.05.2002, p. R360-R362.

Research output: Contribution to journalReview article

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T2 - Bridging the GAP between ARF and Rho

AU - Santy, Lorraine C.

AU - Casanova, James E.

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