GTPase signaling: Bridging the GAP between ARF and Rho

Lorraine C. Santy, James E. Casanova

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Membrane traffic and actin cytoskeleton dynamics are intimately linked, and GTPases of the Rho and ARF families may work together to regulate both. Recent studies have identified a family of GTPase activating proteins (GAPs) that contain both ARF-GAP and Rho-GAP domains, providing the first direct link between these two signaling pathways.

Original languageEnglish (US)
Pages (from-to)R360-R362
JournalCurrent Biology
Volume12
Issue number10
DOIs
Publication statusPublished - May 14 2002

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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