Abstract
For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.
| Original language | English (US) |
|---|---|
| Title of host publication | Medical Imaging 2019 |
| Subtitle of host publication | Image-Guided Procedures, Robotic Interventions, and Modeling |
| Editors | Baowei Fei, Cristian A. Linte |
| Publisher | SPIE |
| ISBN (Electronic) | 9781510625495 |
| DOIs | |
| State | Published - Jan 1 2019 |
| Event | Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States Duration: Feb 17 2019 → Feb 19 2019 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 10951 |
| ISSN (Print) | 1605-7422 |
Conference
| Conference | Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling |
|---|---|
| Country | United States |
| City | San Diego |
| Period | 2/17/19 → 2/19/19 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
Cite this
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Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. / Zhao, Wennan; Bascom, Rebecca; Toth, Jennifer; Higgins, William Evan.
Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. ed. / Baowei Fei; Cristian A. Linte. SPIE, 2019. 109511P (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Guidance system development for radial-probe endobronchial ultrasound bronchoscopy
AU - Zhao, Wennan
AU - Bascom, Rebecca
AU - Toth, Jennifer
AU - Higgins, William Evan
PY - 2019/1/1
Y1 - 2019/1/1
N2 - For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.
AB - For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.
UR - http://www.scopus.com/inward/record.url?scp=85068888756&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068888756&partnerID=8YFLogxK
U2 - 10.1117/12.2505827
DO - 10.1117/12.2505827
M3 - Conference contribution
AN - SCOPUS:85068888756
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2019
A2 - Fei, Baowei
A2 - Linte, Cristian A.
PB - SPIE
ER -