Guidance system development for radial-probe endobronchial ultrasound bronchoscopy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2019
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
EditorsBaowei Fei, Cristian A. Linte
PublisherSPIE
ISBN (Electronic)9781510625495
DOIs
StatePublished - Jan 1 2019
EventMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling - San Diego, United States
Duration: Feb 17 2019Feb 19 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10951
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CitySan Diego
Period2/17/192/19/19

Fingerprint

Bronchoscopy
Ultrasonics
Biopsy
probes
lesions
Physicians
Bronchoscopes
Thoracoscopy
Needle Biopsy
Pneumothorax
physicians
Thorax
pulmonary lesions
Equipment and Supplies
Lung
pneumothorax
methodology
site selection
Research
Site selection

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Zhao, W., Bascom, R., Toth, J., & Higgins, W. E. (2019). Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. In B. Fei, & C. A. Linte (Eds.), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling [109511P] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951). SPIE. https://doi.org/10.1117/12.2505827
Zhao, Wennan ; Bascom, Rebecca ; Toth, Jennifer ; Higgins, William Evan. / Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. editor / Baowei Fei ; Cristian A. Linte. SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
@inproceedings{6cb88cb89a3241aea1eb2b8f609d6667,
title = "Guidance system development for radial-probe endobronchial ultrasound bronchoscopy",
abstract = "For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15{\%} pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.",
author = "Wennan Zhao and Rebecca Bascom and Jennifer Toth and Higgins, {William Evan}",
year = "2019",
month = "1",
day = "1",
doi = "10.1117/12.2505827",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Baowei Fei and Linte, {Cristian A.}",
booktitle = "Medical Imaging 2019",
address = "United States",

}

Zhao, W, Bascom, R, Toth, J & Higgins, WE 2019, Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. in B Fei & CA Linte (eds), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling., 109511P, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10951, SPIE, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling, San Diego, United States, 2/17/19. https://doi.org/10.1117/12.2505827

Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. / Zhao, Wennan; Bascom, Rebecca; Toth, Jennifer; Higgins, William Evan.

Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. ed. / Baowei Fei; Cristian A. Linte. SPIE, 2019. 109511P (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Guidance system development for radial-probe endobronchial ultrasound bronchoscopy

AU - Zhao, Wennan

AU - Bascom, Rebecca

AU - Toth, Jennifer

AU - Higgins, William Evan

PY - 2019/1/1

Y1 - 2019/1/1

N2 - For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.

AB - For peripheral pulmonary lesion diagnosis, surgical thoracoscopy and percutaneous needle biopsy are common invasive options, but entail significant risks; e.g., percutaneous biopsy carries a 15% pneumothorax rate and risk of other complications. The development of new bronchoscopic devices, such as radial-probe endobronchial ultrasound (RP-EBUS), however, enables far less risky lesion diagnosis. Based on recent research, an image-guided bronchoscopy system can be used to navigate the bronchoscope close to the lesion, while RP-EBUS, which provides real-time extraluminal information on local tissue and lesions, can then be used for lesion localization and biopsy site selection. Unfortunately, physician skill in using RP-EBUS varies greatly, especially for physicians not at expert centers. This results in poor biopsy yields. Also, current state-of-the-art image-guided bronchoscopy systems provide no means for guiding the use of the RP-EBUS. We describe progress toward devising a methodology that facilitates synchronization of the known chest CT-based guidance information to possible locations for invoking RP-EBUS. In particular, we describe a top-level CT-based mechanism that mimics the possible positions of the RP-EBUS probe, supplemented with an approach that simulates possible RP-EBUS views. Results with human patient data demonstrate the potential of the methodology.

UR - http://www.scopus.com/inward/record.url?scp=85068888756&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068888756&partnerID=8YFLogxK

U2 - 10.1117/12.2505827

DO - 10.1117/12.2505827

M3 - Conference contribution

AN - SCOPUS:85068888756

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2019

A2 - Fei, Baowei

A2 - Linte, Cristian A.

PB - SPIE

ER -

Zhao W, Bascom R, Toth J, Higgins WE. Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. In Fei B, Linte CA, editors, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. SPIE. 2019. 109511P. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2505827