Gut microbiome as a novel cardiovascular therapeutic target

Vishal Singh, Beng San Yeoh, Matam Vijay-Kumar

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Over the last two decades, our understanding of gut microbiotal composition and its association with intra-intestinal and extra-intestinal diseases including risk factors of cardiovascular disease (CVD) namely metabolic syndrome and atherosclerosis, have been increased exponentially. A pertinent question which often arises in researchers' community is on how to manipulate the gut microbial ecology to 'cure' the cardiovascular risk factors. Accordingly, in this review we summarized the potential strategies, based on our current knowledge on gut microbiota in modulating CVD, how gut microbiota can be therapeutically exploited by targeting their metabolic activity to alleviate the risk factors of CVD.

Original languageEnglish (US)
Pages (from-to)8-12
Number of pages5
JournalCurrent Opinion in Pharmacology
Volume27
DOIs
StatePublished - Apr 1 2016

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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