The B10.SAA48 congenic line was derived by transferring the H‐2 haplotype of a wild mouse onto the background of the inbred strain C57BL/10Sn (abbreviated as B10). The line carries the Dw3 allele in combination with an L allele different from that present in other Dw3 strains. One possible explanation of this finding is that crossing over occurred between the D and L loci. The determinants H‐2.m64 and H‐2.m65 represent an inclusion doublet in which the latter never occurs without the former. Typing of B10.W lines with Ld‐specific CTLs reveals the absence of this allele in all the lines, including those carrying an allele serologically similar to Ld.
|Original language||English (US)|
|Number of pages||7|
|State||Published - Jan 1983|
All Science Journal Classification (ASJC) codes
- Immunology and Allergy