Heart failure in women

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

Congestive heart failure represents a growing health issue with significant morbidity, expense, and mortality. Unfortunately, despite heart failure affecting men and women equally, women historically have represented a minority in heart failure trials. Despite this disparity, treatment decisions rely heavily on these trials. Women with heart failure often have different clinical features than men, such as age of onset and comorbidities. Compared with men, women also demonstrate differences in remodeling and the response to injury, such as volume or pressure overload and myocardial infarction. We are only beginning to understand the clinical implications of these gender differences and their impact on pharmacologic treatments. After discussing these differences, a review of the agents useful in systolic failure is made, including angiotensin-converting enzyme inhibitors, β-blockers, digoxin, and aldosterone inhibition. Treatment of diastolic heart failure with empiric guidelines follows.

Original languageEnglish (US)
Pages (from-to)104-109
Number of pages6
JournalCurrent women's health reports
Volume3
Issue number2
StatePublished - Apr 1 2003

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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