Heart Transplantation for Congenital Heart Disease

Linda B. Pauliks, Akif Undar

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Congenital heart disease affects 0.8% of all live-born infants. Some of the malformed hearts can at best be palliated by conventional surgical or catheter interventions from the start. Others fail slowly from chronic overloading. Patients with congenital heart disease have been among the first transplant recipients since 1967. Primary therapy with infant heart transplant is a convincing concept from an immunological perspective but large-scale implementation is limited by donor organ shortages. Another growing area is rescue therapy for older patients with end-stage heart failure after palliative procedures, particularly those with single-ventricle hearts, systemic right ventricles, and associated arrhythmias.

Original languageEnglish (US)
Pages (from-to)603-608
Number of pages6
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Volume2
Issue number4
DOIs
StatePublished - Jan 1 2011

Fingerprint

Heart Transplantation
Heart Ventricles
Heart Diseases
Cardiac Arrhythmias
Catheters
Heart Failure
Tissue Donors
Transplants
Therapeutics
Transplant Recipients

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Heart Transplantation for Congenital Heart Disease",
abstract = "Congenital heart disease affects 0.8{\%} of all live-born infants. Some of the malformed hearts can at best be palliated by conventional surgical or catheter interventions from the start. Others fail slowly from chronic overloading. Patients with congenital heart disease have been among the first transplant recipients since 1967. Primary therapy with infant heart transplant is a convincing concept from an immunological perspective but large-scale implementation is limited by donor organ shortages. Another growing area is rescue therapy for older patients with end-stage heart failure after palliative procedures, particularly those with single-ventricle hearts, systemic right ventricles, and associated arrhythmias.",
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Heart Transplantation for Congenital Heart Disease. / Pauliks, Linda B.; Undar, Akif.

In: World Journal for Pediatric and Congenital Heart Surgery, Vol. 2, No. 4, 01.01.2011, p. 603-608.

Research output: Contribution to journalReview article

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