Abstract
Congenital heart disease affects 0.8% of all live-born infants. Some of the malformed hearts can at best be palliated by conventional surgical or catheter interventions from the start. Others fail slowly from chronic overloading. Patients with congenital heart disease have been among the first transplant recipients since 1967. Primary therapy with infant heart transplant is a convincing concept from an immunological perspective but large-scale implementation is limited by donor organ shortages. Another growing area is rescue therapy for older patients with end-stage heart failure after palliative procedures, particularly those with single-ventricle hearts, systemic right ventricles, and associated arrhythmias.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 603-608 |
| Number of pages | 6 |
| Journal | World Journal for Pediatric and Congenital Heart Surgery |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 2011 |
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All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Surgery
- Medicine(all)
- Cardiology and Cardiovascular Medicine
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Heart Transplantation for Congenital Heart Disease. / Pauliks, Linda B.; Undar, Akif.
In: World Journal for Pediatric and Congenital Heart Surgery, Vol. 2, No. 4, 01.01.2011, p. 603-608.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Heart Transplantation for Congenital Heart Disease
AU - Pauliks, Linda B.
AU - Undar, Akif
PY - 2011/1/1
Y1 - 2011/1/1
N2 - Congenital heart disease affects 0.8% of all live-born infants. Some of the malformed hearts can at best be palliated by conventional surgical or catheter interventions from the start. Others fail slowly from chronic overloading. Patients with congenital heart disease have been among the first transplant recipients since 1967. Primary therapy with infant heart transplant is a convincing concept from an immunological perspective but large-scale implementation is limited by donor organ shortages. Another growing area is rescue therapy for older patients with end-stage heart failure after palliative procedures, particularly those with single-ventricle hearts, systemic right ventricles, and associated arrhythmias.
AB - Congenital heart disease affects 0.8% of all live-born infants. Some of the malformed hearts can at best be palliated by conventional surgical or catheter interventions from the start. Others fail slowly from chronic overloading. Patients with congenital heart disease have been among the first transplant recipients since 1967. Primary therapy with infant heart transplant is a convincing concept from an immunological perspective but large-scale implementation is limited by donor organ shortages. Another growing area is rescue therapy for older patients with end-stage heart failure after palliative procedures, particularly those with single-ventricle hearts, systemic right ventricles, and associated arrhythmias.
UR - http://www.scopus.com/inward/record.url?scp=84992905522&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84992905522&partnerID=8YFLogxK
U2 - 10.1177/2150135111410078
DO - 10.1177/2150135111410078
M3 - Review article
AN - SCOPUS:84992905522
VL - 2
SP - 603
EP - 608
JO - World Journal for Pediatric and Congenital Hearth Surgery
JF - World Journal for Pediatric and Congenital Hearth Surgery
SN - 2150-1351
IS - 4
ER -