Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer

Alireza Aminsharifi, Steven C. Brousell, Andrew Chang, Juan León, Brant A. Inman

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Disease recurrence and progression remain as significant challenges for the management of non-muscle invasive bladder cancer (NMIBC). In recent years, novel drugs and delivery systems have been investigated as strategies to reduce recurrence, progression and mortality. In this review, we focus on the role of intravesical hyperthermic chemotherapy and discuss a novel approach involving a heat-activated drug delivery system (ThermoDox) that enables local accumulation of systemic chemotherapy.

Original languageEnglish (US)
Pages (from-to)447-452
Number of pages6
JournalArchivos Espanoles de Urologia
Volume71
Issue number4
StatePublished - May 2018

All Science Journal Classification (ASJC) codes

  • Urology

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