Hematopoietic Stem Cell Transplant Candidate and Designated Proxy Distress Levels Prior to Hematopoietic Stem Cell Transplantation

Katharine E. Duckworth, Allison M. Forti, Gregory B. Russell, Seema Naik, David D. Hurd, Richard P. McQuellon

Research output: Contribution to journalArticle

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Hematopoietic stem cell transplantation (HCT) is associated with a high risk of morbidity, making advance care planning (ACP) essential. The purpose of this study was to assess and compare proxy and HCT candidate distress levels (Distress Thermometer) before (T1) and after (T2) ACP question completion. 79 participants (40 HCT candidates, 39 proxies) rated their distress. The T1, T2 mean distress scores (SD) for HCT candidates were 3.13(2.27), 2.96(2.10); 43% and 38% endorsed clinically significant distress (≥4). Proxies reported 4.21(2.48), 4.33 (2.46); 62% endorsed significant distress at T1, T2. The majority of proxies endorsed distress levels that were clinically significant and comparatively higher (T1 (p = 0.047) and T2 (p = 0.009)) than their paired HCT recipients. Responding to questions about ACP did not increase overall distress ratings.

Original languageEnglish (US)
Pages (from-to)853-856
Number of pages4
JournalAmerican Journal of Hospice and Palliative Medicine
Issue number8
Publication statusPublished - Dec 10 2014


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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