Hemodynamic Effects of Volume Expansion and Nitroprusside Compared with Pericardiocentesis in Patients with Acute Cardiac Tamponade

Richard E. Kerber, Joseph Gascho, Robert Litchfield, Paul Wolfson, David Ott, Natesa G. Pandian

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Acute cardiac tamponade is a medical emergency that requires urgent therapy. Removal of pericardial fluid by pericardiocentesis or by open surgical drainage is effective,1 2 3 but delays may occur while the catheterization laboratory or operating room is being prepared. Alternative methods would be useful as interim therapy, if they were also effective. The time-honored emergency therapy for acute cardiac tamponade is intravascular volume expansion.1,2,4 5 6 Vasodilator drugs have also been recommended, especially in combination with volume expansion.7,8 These recommendations are, however, based on studies in animals.7 8 9 10 11 There is a surprising paucity of relevant data on human beings, and this may be important.

Original languageEnglish (US)
Pages (from-to)929-931
Number of pages3
JournalNew England Journal of Medicine
Volume307
Issue number15
DOIs
StatePublished - Oct 7 1982

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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